IVANO Bioscience


Provider of validated pseudotyped viral particles, cell-free neutralization assay kits, and AAV packaging cell line technology for infectious disease research and gene therapy R&D. Offers custom pseudovirus production, per-batch functional quality control with accessible CoA and SDS documentation, and assays designed for BSL-2 or lower laboratory workflows.

Industries

Analytics
Biopharma
Biotechnology
Test and Measurement
Biotechnology Research

Nr. of Employees

small (1-50)

IVANO Bioscience


Products

Catalog of validated pseudotyped viral particles

Ready-to-use replication-defective pseudotyped particles displaying variant- or strain-specific viral envelope proteins for use in neutralization and infectivity assays; offered with reporter genes (luciferase default, GFP optional) and per-batch QC documentation (CoA and SDS).

Cell-free neutralization assay kit

Reagent kit that reproduces key virus–cell interactions using engineered particle components to detect functional neutralizing antibodies without live virus or cell culture; designed for rapid, mix-and-read workflows compatible with automated workstations.

rAAV packaging cell line platform

HEK293-based packaging cell line technology to generate AAV producer lines and produce recombinant AAV vectors for preclinical research, intended to reduce dependence on transient transfection methods.

SARS-CoV-2 Pseudovirus

Comprehensive neutralization assay solution pseudotyped with the Spike Glycoprotein of SARS-CoV-2 virus, Delta (B.1.617.2) variant, carrying a modified genome that expresses a luciferase reporter gene.

SARS-CoV-2 Pseudoviruses

SARS-CoV-2 pseudovirus reagents utilizing 3rd generation lentiviral vector and luciferase reporter system for neutralization assays.

SARS-CoV-2 Pseudovirus, BA.1 (Omicron) variant

SARS-CoV-2 pseudovirus featuring the Omicron (BA.1) variant spike glycoprotein and a firefly luciferase reporter, validated for transduction efficiency and neutralization assays.

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Services

Feasibility assessment, production-parameter definition, scale-up testing, and manufacture of custom pseudotyped viral particles for neutralization and infectivity assays; options for co-development and special pricing for select projects.

Expertise Areas

  • Pseudotyped viral particle manufacturing
  • Variant- and strain-specific pseudovirus productization
  • Neutralization assay development (cell-free and cell-based)
  • AAV packaging cell line development
  • Show More (3)

Key Technologies

  • Pseudotyped lentiviral particles
  • VSV-based pseudovirus systems
  • Virus-like particle components for cell-free assays
  • Reporter gene assays (luciferase, GFP)
  • Show More (3)

News & Updates

References to peer-reviewed articles that used pseudovirus neutralization assays as BSL-2-compatible methods for evaluating neutralizing antibodies and vaccine immunogenicity.


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