Sexton Biotechnologies
Sexton Biotechnologies specializes in manufacturing solutions for the cell and gene therapy industry, focusing on innovative bioproduction tools, automation systems, and process handling products to enhance clinical and commercial cell therapy manufacturing processes. The company is committed to developing flexible automation and scalable production systems, including the Signata CT-5 and automated thawing systems, to meet the evolving needs of the regenerative medicine field. It also offers a range of process and handling products such as the AF-500 Automated Fill & Seal System, CellSeal Cryogenic Vials, Freezing Containers, Radio Frequency Tube Sealing, and Signata CT-5, supporting various stages of cell therapy manufacturing from starting materials to downstream use.
Industries
Nr. of Employees
small (1-50)
Sexton Biotechnologies
1102 Indiana Avenue, Indianapolis, IN 46202, U.S.A.
Patents
Products
Pathogen-reduced human platelet lysate formulations
Human platelet-derivative supplements processed with validated pathogen-inactivation methods for use as cell-culture supplements and in clinical manufacturing workflows; characterized for lot consistency and frozen-storage stability.
Xeno-free platelet-derived culture supplements
Human platelet-derived supplements formulated as animal-component-free alternatives for cell culture and cryopreservation support, intended for use in automated and bioreactor expansion workflows.
Platelet-lysate formulations for immune-cell expansion
Platelet-derivative formulation intended for propagation and expansion of lymphocytes and other immune cells as an alternative to serum.
Automated closed-system fill–finish and fluid-management platforms
Flexible automated platforms designed to support closed connections across unit operations and protocol-driven control for small-to-mid scale cell and gene therapy manufacturing, with capabilities to integrate with bioreactors and downstream automation.
Automated fill-and-seal equipment
Automated equipment for filling and sealing vials, tubes and tubing to support fill–finish operations and closed-system handling.
Closed-access cryogenic vials, adapters and freezing containers
Cryogenic vials, adapters and compatible freezing containers and racks that enable closed-system access and controlled cryogenic storage for cells and biological materials.
Pathogen-reduced human platelet lysate formulations
Human platelet-derivative supplements processed with validated pathogen-inactivation methods for use as cell-culture supplements and in clinical manufacturing workflows; characterized for lot consistency and frozen-storage stability.
Xeno-free platelet-derived culture supplements
Human platelet-derived supplements formulated as animal-component-free alternatives for cell culture and cryopreservation support, intended for use in automated and bioreactor expansion workflows.
Platelet-lysate formulations for immune-cell expansion
Platelet-derivative formulation intended for propagation and expansion of lymphocytes and other immune cells as an alternative to serum.
Automated closed-system fill–finish and fluid-management platforms
Flexible automated platforms designed to support closed connections across unit operations and protocol-driven control for small-to-mid scale cell and gene therapy manufacturing, with capabilities to integrate with bioreactors and downstream automation.
Automated fill-and-seal equipment
Automated equipment for filling and sealing vials, tubes and tubing to support fill–finish operations and closed-system handling.
Closed-access cryogenic vials, adapters and freezing containers
Cryogenic vials, adapters and compatible freezing containers and racks that enable closed-system access and controlled cryogenic storage for cells and biological materials.
Services
Customer-facing technical support for product selection, protocol questions and integration of process hardware and supplements into manufacturing workflows.
Development and provision of protocol sets, user guides, instructional videos and demonstration workflows to support integration of automated fill–finish and closed fluid-management systems.
Customer-facing technical support for product selection, protocol questions and integration of process hardware and supplements into manufacturing workflows.
Development and provision of protocol sets, user guides, instructional videos and demonstration workflows to support integration of automated fill–finish and closed fluid-management systems.
Expertise Areas
- Human platelet lysate manufacturing and characterization
- Pathogen inactivation and validation for blood-derived supplements
- Closed-system automation and fill–finish for cell and gene therapy
- Bioreactor-compatible cell expansion and scale-up
Key Technologies
- Human platelet lysate production
- Pathogen-reduction technologies (e-beam, UV, gamma irradiation)
- Closed-access cryogenic vial and adapter systems
- Automated fill–finish and closed fluid-management platforms