Instituto Grifols, S.A.


Grifols is a global healthcare company dedicated to improving people's health and well-being through innovative medicines, solutions, and services. With a history dating back to 1909, Grifols specializes in plasma-derived products, diagnostics, and biopharmaceuticals, and is committed to scientific innovation, sustainability, and long-term partnerships. The company develops a wide range of products and solutions including plasma, immunoglobulins, fibrinogen, and advanced diagnostic systems, with a strong focus on safety, innovation, and improving patient outcomes.

Industries

biotechnology
health-care
manufacturing

Nr. of Employees

Very Large (1000+)

Instituto Grifols, S.A.

Barcelona, Catalonia, Spain, Europe


Patents

Container for a solution of human plasma proteins and method for obtaining thereof

US-11458070-B2

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Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria

US-11116765-B2

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Concentrated, inhalable ciprofloxacin formulation

US-11026941-B2

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Method and device for treating blood cholesterol disorders

US-10624924-B2

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Container for a solution of human plasma proteins and method for obtaining thereof

US-10624814-B2

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Method for the preparation of human albumin with reduced level of dissolved oxygen

US-10350274-B2

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Products

Automated frozen-container thawing and emptying system

Transportable tunnel-based system that performs localized thawing, washing, drying, cutting and robotic emptying of frozen containers into processing tanks while separating disposable waste.

Vacuum-assisted flexible-container filling machine

Machine for filling flexible parenteral bags using a mold and controlled vacuum to minimize particulate generation and simplify sealing for compatibility with sterilization.

Sterile small-container filling system with pre-sterilized stopper workflow

Aseptic filling equipment using pre-assembled sterilized stoppers and caps combined with laminar airflow and in-line weight verification for vial and small-container filling.

Micro-hematocrit centrifuge and consumables

Compact micro-hematocrit centrifuge units, compatible capillary tubes and readers for rapid, low-volume hematocrit measurement in clinical settings.

Gel-card incubator and modular incubation systems

Incubator devices and modular systems designed to standardize temperature-controlled and timed incubation for gel-column agglutination workflows and to facilitate integration into automated analyzers.

Hospital pharmacy and blood bank software suite

Software suite for pharmacy logistics, inventory management, medication dispensing, blood bank management and clinical-trial data management, available as on-premise or web-based deployments.

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Services

Design and implementation of plasma fractionation process improvements, including jacketed vessel integration, clean-zone optimization and reactor mounting solutions delivered as basic engineering or turnkey implementation with start-up support.

Engineering and consulting services for aseptic filling operations, including pre-assembly and sterilization workflows, laminar airflow design, vacuum-assisted bag filling process guidance and load-cell integration for fill verification.

Deployment and integration of automated central storage carousels and ward-level dispensing cabinets, plus training and user support to implement closed, unit-dose dispensing and real-time inventory control.

Development, customization and deployment of software for hospital pharmacy inventory, medication dispensing, blood bank management and clinical-trial record integration, including web-based deployment options.

Advisory and implementation services for establishing blood bank operations, including collection protocols, typing and storage workflows, donor recruitment practices and plasmapheresis deployment.

In-house engineering consultancy offering facility design, clean-zone supply and assembly, sterile filling equipment and turnkey plant implementation for third parties.

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Expertise Areas

  • Aseptic filling and sterile manufacturing of parenteral products
  • Flexible-container design and polymeric packaging for intravenous use
  • Plasma fractionation process engineering and facility scale-up
  • Automated thawing and robotic handling for frozen biological containers
  • Show More (9)

Key Technologies

  • Vacuum-assisted flexible-bag filling
  • Multi-layer polymeric bag packaging with integrated ports
  • Autoclave sterilization and pressure-control strategies
  • Localized thaw tunnels with robotic emptying
  • Show More (14)

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