Scarab Genomics LLC.


Provider of engineered reduced-genome Escherichia coli hosts, ancillary expression tools, and a continuous fermentation platform to support high-efficiency production of recombinant proteins and nucleic acids. Offers a catalog of host strains with targeted genetic deletions (e.g., removal of insertion sequences, proteases, toxin-antitoxin pairs, methylases), research-use vaccine carrier proteins, analytical kits, licensing options, and technical support for strain selection and process development.

Industries

biotechnology
health-care
medical

Nr. of Employees

small (1-50)

Scarab Genomics LLC.

Madison, Wisconsin, United States, North America


Products

Catalog of reduced-genome E. coli production strains

A catalog of engineered reduced-genome E. coli strains with variants including recA deletions, low-mutator backgrounds, T7-compatible strains, low-endotoxin modifications, methylation-deficient variants, protease-deletion libraries, toxin-antitoxin deletions and reduced E. coli Nissle 1917 derivatives.

Vaccine carrier proteins for research

Research-grade carrier proteins used in conjugate vaccine research and development, supplied with purification methods described.

Expression vector (pSX2) for host strains

An expression vector product intended to improve cloning and expression of target genes in the company's host strains.

Insertion sequence detection kit

An analytical kit to detect insertion sequence contamination in DNA preparations.

Continuous fermentation platform (C-Flow) - licensing

A process and system for extended continuous fermentation intended to increase efficiency and consistency of biopharmaceutical production; available via licensing.


Services

Licensing and technical consulting

Commercial licensing of engineered host strains and continuous fermentation process; advisory support on strain selection and expression conditions for specific targets.

Expertise Areas

  • Strain engineering for production hosts
  • Bioprocessing and continuous fermentation
  • Recombinant protein expression and purification
  • Plasmid and nucleic acid production
  • Show More (3)

Key Technologies

  • Reduced-genome bacterial host engineering
  • Extended continuous fermentation / continuous flow bioprocessing
  • Plasmid production and purification
  • High-yield dsRNA and small RNA synthesis
  • Show More (4)

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