Sandia Biotech, Inc.


SandiaBio is a biotechnology research partner specializing in fluorescent reagents, protein analysis, diagnostic tools, and innovative technologies such as split GFP systems, FluorAbodies, and protease activity kits. They develop and offer advanced products to enhance scientific discovery, diagnostics, and cellular imaging, with a focus on high-quality, recombinant, and fluorescent antibody derivatives and protein tools.

Industries

biotechnology
life-science
product-research
wellness

Nr. of Employees

small (1-50)

Sandia Biotech, Inc.


Patents

Systematic creation of fluorescent fusion polypeptides

US-11702766-B2

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Products

Recombinant intrinsically fluorescent antibody probes

Monovalent single-chain antibody fragments genetically fused to fluorescent protein reporters for direct staining and detection in microscopy and flow cytometry.

Split-fluorescent protein detection reagents

Ready-to-use complementary detector fragments supplied as solutions to reconstitute fluorescence upon complementation with small peptide tags for folding and solubility assays.

Multi-color universal detection reagents

Color-specific detector reagents for use with split fluorescent-protein complementation assays to enable multi-color readouts.

Split-fluorescent protein solubility and folding assay kits (bacterial and mammalian)

Kits that use split-fluorescent protein complementation to assess solubility and correct folding of tagged proteins in bacterial or mammalian expression systems.

Stabilized fluorescent protein expression plasmid

Expression-ready plasmid encoding a stabilized fluorescent protein reporter for fusion-protein constructs and reporter assays.

Peptide tag plasmids for complementation assays (bacterial and mammalian)

Plasmids encoding short complementation tags for tagging proteins to enable split-fluorescent protein detection in bacterial or mammalian cells.

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Services

Custom design and manufacture of recombinant intrinsically fluorescent antibody probes with support for OEM arrangements and partner distribution.

Support for licensing arrangements and collaborative development with academic technology transfer organizations and research institutions to enable commercialization.

Expertise Areas

  • Recombinant fluorescent antibody engineering
  • Fluorescent protein engineering and stabilized reporter design
  • Split-fluorescent protein complementation assays for folding and interaction analysis
  • Protease activity mapping and protease-specific assay development
  • Show More (6)

Key Technologies

  • Fluorescent protein fusions and stabilized variants
  • Split fluorescent protein complementation
  • Tethered split-protein substrates enabling latent fluorophore activation by proteolysis
  • Protease-specific fluorescent substrates
  • Show More (4)

News & Updates

Our technologies harness the biological properties of fluorescent proteins and expand their application capabilities. Fluorescent proteins have revolutionized biomedical research, enabling real-time visualization of cellular processes. This article discusses the history, structure, and engineering of fluorescent proteins, including split GFP technology and FluorAbodies.

Learn about SandiaBio's location in Albuquerque, NM, and their focus on cancer diagnostics, therapeutics, and proprietary antibody and protein reagents for biomedical research.

Development of fluorescent antibody derivatives that are recombinant, small, highly specific, and suitable for flow cytometry, imaging, and research applications. The article covers the structure, advantages, and applications of FluorAbodies.


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