Profusa


Developer of tissue-integrated, injectable hydrogel microsensors and associated optical readers and data systems for long-term, continuous monitoring of body chemistry. Products and programs include clinical tissue-oxygen monitoring (CE marked in the EU), development of long-duration glucose and multi-analyte sensors, wearable/patch reader development, and a cloud/AI data platform for secure clinical integration. Work has been supported by DARPA, NIH, and other grants.

Industries

Biotechnology
Finance
Financial Services
Health Care
Medical
Medical Device
Personal Health
Sensor
Wellness
Medical Equipment Manufacturing

Nr. of Employees

medium (51-250)

Profusa

Emeryville, California, United States


Patents

Near-IR glucose sensors

US-12285250-B2

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Optical filter device, system, and methods for improved optical rejection of high angle of incidence (AOI) light

US-12204125-B2

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Method and device for correcting optical signals

US-12059254-B2

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Oxygen sensors

US-12048535-B2

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Multi-analyte sensing tissue-integrating sensors

US-11903702-B2

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Polymerizable near-IR dyes

US-11866588-B2

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Products

Lumee Oxygen Platform

Integrated system comprising injectable oxygen-sensitive hydrogel biosensors, an injector, an external optical reader, and software for encrypted data capture and historical tracking of local tissue oxygen.


Services

Co-development partnerships with academic centers and industry to develop readers, thin-film electronics, and clinical applications for implantable biosensors.

Support and execution of clinical studies for device evaluation and evidence generation in vascular interventions, wound care, and other intended-use scenarios.

Expertise Areas

  • Tissue-integrated biosensors
  • Continuous biochemical monitoring
  • Optical detection and tissue optics
  • Clinical device evaluation for vascular and wound care
  • Show More (4)

Key Technologies

  • Injectable hydrogel microsensors
  • Fluorescence-based luminescent sensing
  • Optical reader technology
  • Wearable thin-film electronics (patch readers)
  • Show More (4)

News & Updates

Public demonstrations of biointegrated sensors and presentations on long-term continuous monitoring at CES and related events.

Media articles describing the injectable biosensor concept, continuous biochemical monitoring, and demonstrations at CES and other events.

Received CE Mark to market the tissue-oxygen monitoring platform in Europe.

Awarded $7.5M DARPA/ARO grant to develop implantable biosensors for simultaneous, continuous monitoring of multiple body chemistries.

Awarded $1.5M NIH Phase II SBIR grant in collaboration with NC State ASSIST Center to co-develop an ultrathin, wearable wireless oxygen monitor (bandage reader) for PAD patients.

Received a 2016 Edison Silver Award in the Health and Wellness – Wearable and Sensors category for tissue-integrating biosensor design and technology.

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