Nordic Preclinical Sciences
Nordic Preclinical Sciences AB is a CRO specializing in proteomics and in vivo services, dedicated to supporting drug discovery and development through advanced, flexible, and tailored laboratory techniques. Their mission is to revolutionize drug discovery research by providing cutting-edge, affordable pre-clinical services, making high-end methods accessible to sponsors worldwide. They aim to be a trusted partner, delivering high-quality science that positively impacts clinical success, with a focus on collaboration, innovation, and expertise in therapeutic areas such as oncology, immunology, respiratory, neurological, cardiovascular, kidney diseases, and more.
Industries
Nr. of Employees
small (1-50)
Nordic Preclinical Sciences
Karolinska Science Park, Solna, Stockholm, Sweden
Products
Proteome-signature reference library for anticancer compound responses
A curated proteome-signature database of anticancer molecule responses used to compare new proteomic profiles for mechanism-of-action discovery and target prioritization.
Proteome-signature reference library for anticancer compound responses
A curated proteome-signature database of anticancer molecule responses used to compare new proteomic profiles for mechanism-of-action discovery and target prioritization.
Services
End-to-end laboratory services including cell culture sample preparation, protein extraction, automated digestion, peptide fractionation, and high-resolution LC‑MS/MS runs.
Services to identify drug targets and mechanisms of action using compound-specific proteome responses, affinity-capture approaches and orthogonal MS-based deep proteomics.
High-throughput expression-proteomics service using compound-induced proteome changes across panels of cell lines to rank likely targets and infer mechanisms.
Comparative service that matches new proteome profiles against an existing proteome-signature library to identify compounds with similar mechanisms and to prioritize targets.
HDX-MS-based structural and dynamic analysis for mapping interaction sites, epitope mapping, and monitoring conformational changes in solution.
TMT/isobaric and label-free quantitative proteomics, plus targeted assays (PRM and triggered targeted workflows) for plasma, serum and cellular samples.
End-to-end laboratory services including cell culture sample preparation, protein extraction, automated digestion, peptide fractionation, and high-resolution LC‑MS/MS runs.
Services to identify drug targets and mechanisms of action using compound-specific proteome responses, affinity-capture approaches and orthogonal MS-based deep proteomics.
High-throughput expression-proteomics service using compound-induced proteome changes across panels of cell lines to rank likely targets and infer mechanisms.
Comparative service that matches new proteome profiles against an existing proteome-signature library to identify compounds with similar mechanisms and to prioritize targets.
HDX-MS-based structural and dynamic analysis for mapping interaction sites, epitope mapping, and monitoring conformational changes in solution.
TMT/isobaric and label-free quantitative proteomics, plus targeted assays (PRM and triggered targeted workflows) for plasma, serum and cellular samples.
Expertise Areas
- Chemical proteomics and target deconvolution
- Quantitative proteomics (isobaric and label-free)
- Protein structural analysis (HDX-MS and binding-site mapping)
- Post-translational modification analysis
Key Technologies
- Hydrogen–deuterium exchange mass spectrometry (HDX-MS)
- High-resolution nanoLC‑MS/MS
- Isobaric labelling (multiplex isobaric tagging, up to 16-plex)
- Label-free quantitative proteomics
News & Updates
Support from the Swedish Government Agency Arbetsförmedlingen through the Starta Eget program, including business advice and collaboration opportunities.
Support from the Swedish Government Agency Arbetsförmedlingen through the Starta Eget program, including business advice and collaboration opportunities.