Miromatrix Medical
Miromatrix is dedicated to eliminating the organ transplant waitlist by developing fully transplantable human organs using proprietary bioengineering technology. Founded in 2009 from the University of Minnesota's research, the company leverages perfusion decellularization and recellularization techniques to create bioengineered organs, aiming to provide new options for transplantation and address the critical shortage of donor organs.
Industries
Nr. of Employees
Very Large (1000+)
Miromatrix Medical
Eden Prairie, Minnesota, United States, North America
Products
Bioengineered extracorporeal liver assist system (single-use organ cartridge plus blood circuit)
A single-use bioengineered liver unit integrated with an extracorporeal blood circuit intended to provide external liver support for acute liver failure patients.
Transplantable bioengineered kidney (preclinical)
Preclinical program to create transplantable kidneys by decellularizing porcine kidneys and recellularizing with human cells to restore renal function.
Transplantable bioengineered liver (preclinical)
Program to create transplantable livers using decellularized porcine liver scaffolds recellularized with human hepatocytes and vascular cells; includes demonstration of function in large-animal models.
Bioengineered extracorporeal liver assist system (single-use organ cartridge plus blood circuit)
A single-use bioengineered liver unit integrated with an extracorporeal blood circuit intended to provide external liver support for acute liver failure patients.
Transplantable bioengineered kidney (preclinical)
Preclinical program to create transplantable kidneys by decellularizing porcine kidneys and recellularizing with human cells to restore renal function.
Transplantable bioengineered liver (preclinical)
Program to create transplantable livers using decellularized porcine liver scaffolds recellularized with human hepatocytes and vascular cells; includes demonstration of function in large-animal models.
Services
Bioengineering of transplantable organs
Research and development of whole-organ bioengineering using perfusion decellularization and recellularization to create transplantable organ grafts.
Development of extracorporeal bioengineered organ support systems
Design and development of single-use bioengineered organ units integrated with extracorporeal blood circuits for temporary organ support.
Preclinical and translational study execution
Conduct of preclinical studies including large-animal transplantation, functional assessment, and safety evaluation to support clinical translation.
Bioengineering of transplantable organs
Research and development of whole-organ bioengineering using perfusion decellularization and recellularization to create transplantable organ grafts.
Development of extracorporeal bioengineered organ support systems
Design and development of single-use bioengineered organ units integrated with extracorporeal blood circuits for temporary organ support.
Preclinical and translational study execution
Conduct of preclinical studies including large-animal transplantation, functional assessment, and safety evaluation to support clinical translation.
Expertise Areas
- Whole-organ bioengineering
- Perfusion decellularization and recellularization
- Extracellular matrix scaffold development
- Bioreactor-based tissue maturation
Key Technologies
- Perfusion decellularization
- Perfusion recellularization
- Bioreactor perfusion culture
- Porcine-derived extracellular matrix scaffolds