Trestle Biotherapeutics
Trestle Biotherapeutics is dedicated to developing bioengineered therapies for patients with kidney failure, aiming to create implantable tissues that can replace dialysis and delay transplantation. Their mission is to transform the lives of patients suffering from organ failure through innovative stem cell biology and 3D biofabrication technologies, bridging scientific disciplines and global expertise to advance regenerative medicine.
Industries
Nr. of Employees
small (1-50)
Trestle Biotherapeutics
San Diego, California, United States, North America
Products
Implantable stem cell‑derived bioengineered kidney tissue (preclinical)
A preclinical-stage, stem cell-derived biofabricated tissue construct intended as an implantable therapeutic to restore renal function and reduce reliance on dialysis.
Implantable stem cell‑derived bioengineered kidney tissue (preclinical)
A preclinical-stage, stem cell-derived biofabricated tissue construct intended as an implantable therapeutic to restore renal function and reduce reliance on dialysis.
Services
Research collaboration for vascular integration
Collaborative research agreements to explore integration of engineered vascular conduits with biofabricated kidney tissues to enable perfusion and vascularization.
Licensing and technology commercialization
Acquisition and commercialization of academic stem cell and biofabrication technologies via license agreements to support product development.
Research collaboration for vascular integration
Collaborative research agreements to explore integration of engineered vascular conduits with biofabricated kidney tissues to enable perfusion and vascularization.
Licensing and technology commercialization
Acquisition and commercialization of academic stem cell and biofabrication technologies via license agreements to support product development.
Expertise Areas
- Bioengineered therapies for kidney disease
- Kidney organoid development
- Stem cell differentiation and reprogramming
- 3D biofabrication and bioprinting
Key Technologies
- 3D bioprinting (cellular extrusion)
- Organoid culture and maturation
- Pluripotent stem cell differentiation to renal lineages
- Automated high-throughput bioprinting