Innovative BioTherapies


A for‑profit biomedical company (founded 2003) focused on research and development of bioengineered organ-replacement devices and cell-based therapeutic platforms. Work centers on isolation and expansion of adult progenitor cells, integration of biomaterials and MEMS into extracorporeal devices, preclinical animal testing, and advancement of technologies toward IND-enabling studies. Research has been supported primarily by federal grants and SBIR awards.

Industries

biotechnology
life-science
medical

Nr. of Employees

small (1-50)

Innovative BioTherapies

401 W Morgan Rd, Ann Arbor, Washtenaw, Michigan 48108 (as indicated in embedded map)


Patents

Cytopheresis cartridges and use thereof

US-11866730-B2

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Cartridge and method for increasing myocardial function

US-11439739-B2

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Cytopheresis cartridges and use thereof

US-11118162-B2

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Cartridge and method for increasing myocardial function

US-10722637-B2

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Cartridge and method for increasing myocardial function

US-10695482-B2

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Products

Wearable extracorporeal renal epithelial cell system (bioartificial kidney)

A wearable extracorporeal device that incorporates adult renal progenitor cells to provide renal epithelial cell functions for acute and chronic renal support.

Pancreatic islet cell-based glucose-regulating device

A cell-based device using pancreatic islet cells to regulate blood glucose by replicating natural insulin production responses.

Extracorporeal immunomodulatory device for acute inflammatory conditions

A blood-contacting device that sequesters and reduces activity of inflammatory cells such as leukocytes and platelets to mitigate life‑threatening inflammation.

Enhanced cell propagation method for device manufacturing

A methodology for isolation and expansion of cells that enables generation of large numbers of therapeutic cells and supports scaled production of cell-containing devices.


Services

On-site veterinary surgical services and large-animal model implementation to support preclinical evaluation of cell-based and extracorporeal devices.

Expertise Areas

  • Bioartificial organ development
  • Cell isolation and large-scale propagation
  • Tissue engineering and regenerative medicine
  • Preclinical large-animal models and veterinary surgical support
  • Show More (5)

Key Technologies

  • Adult progenitor cell isolation
  • Large-scale cell propagation methods
  • Microelectromechanical systems (MEMS)
  • Biomaterials for blood-contacting devices
  • Show More (4)

News & Updates

Recruited as an anchor affiliate company at a regional regenerative medicine center intended to create a cluster for cell-based therapeutic development.

Company founder holds a large number of patents (leadership reports dozens of issued or pending patents related to organ replacement and related technologies).


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