Innovative BioTherapies
A for‑profit biomedical company (founded 2003) focused on research and development of bioengineered organ-replacement devices and cell-based therapeutic platforms. Work centers on isolation and expansion of adult progenitor cells, integration of biomaterials and MEMS into extracorporeal devices, preclinical animal testing, and advancement of technologies toward IND-enabling studies. Research has been supported primarily by federal grants and SBIR awards.
Industries
Nr. of Employees
small (1-50)
Innovative BioTherapies
Ann Arbor, Michigan, United States, North America
Products
Wearable extracorporeal renal epithelial cell system (bioartificial kidney)
A wearable extracorporeal device that incorporates adult renal progenitor cells to provide renal epithelial cell functions for acute and chronic renal support.
Pancreatic islet cell-based glucose-regulating device
A cell-based device using pancreatic islet cells to regulate blood glucose by replicating natural insulin production responses.
Extracorporeal immunomodulatory device for acute inflammatory conditions
A blood-contacting device that sequesters and reduces activity of inflammatory cells such as leukocytes and platelets to mitigate life‑threatening inflammation.
Enhanced cell propagation method for device manufacturing
A methodology for isolation and expansion of cells that enables generation of large numbers of therapeutic cells and supports scaled production of cell-containing devices.
Wearable extracorporeal renal epithelial cell system (bioartificial kidney)
A wearable extracorporeal device that incorporates adult renal progenitor cells to provide renal epithelial cell functions for acute and chronic renal support.
Pancreatic islet cell-based glucose-regulating device
A cell-based device using pancreatic islet cells to regulate blood glucose by replicating natural insulin production responses.
Extracorporeal immunomodulatory device for acute inflammatory conditions
A blood-contacting device that sequesters and reduces activity of inflammatory cells such as leukocytes and platelets to mitigate life‑threatening inflammation.
Enhanced cell propagation method for device manufacturing
A methodology for isolation and expansion of cells that enables generation of large numbers of therapeutic cells and supports scaled production of cell-containing devices.
Services
Preclinical study and veterinary surgical support
On-site veterinary surgical services and large-animal model implementation to support preclinical evaluation of cell-based and extracorporeal devices.
Preclinical study and veterinary surgical support
On-site veterinary surgical services and large-animal model implementation to support preclinical evaluation of cell-based and extracorporeal devices.
Expertise Areas
- Bioartificial organ development
- Cell isolation and large-scale propagation
- Tissue engineering and regenerative medicine
- Preclinical large-animal models and veterinary surgical support
Key Technologies
- Adult progenitor cell isolation
- Large-scale cell propagation methods
- Microelectromechanical systems (MEMS)
- Biomaterials for blood-contacting devices