Michigan Diagnostics LLC
US-based manufacturer and distributor of research and diagnostic reagents since 1998. Operates a domestic manufacturing facility producing chromogenic and chemiluminescent enzyme substrates, cyclodextrin excipients and derivatives, fluorescent labels, antibodies, affinity resins, and specialty chemicals. Provides custom synthesis and conjugation services, lot-specific analytical documentation (COA, SDS, HPLC, NMR), ISO 13485–aligned quality systems and regulatory support for clinical-use products, and domestic OEM/bulk supply with temperature-controlled logistics.
Industries
N/A
Nr. of Employees
small (1-50)
Patents
Composition comprising red cell-derived microparticles and method of treating excessive bleeding
US-11241457-B2
View Details
Composition comprising red cell-derived microparticles and method of treating excessive bleeding
US-11241457-B2
View DetailsProducts
Chromogenic and chemiluminescent substrates
Reagents for enzyme-based detection (peroxidase and alkaline phosphatase) formulated for ELISA, Western blot and membrane assays with options for single-bottle ready-to-use formats and two-component systems.
Cyclodextrins and derivatives
Native and modified alpha, beta and gamma cyclodextrins and derivatives for solubility enhancement, inclusion complexation and formulation use; supplied with analytical data and flexible packaging sizes.
Fluorescent dyes and reactive labels
High-purity fluorescent compounds and reactive esters for labeling proteins, peptides and nucleic acids used in imaging and assay development.
Antibodies and immunoreagents
Polyclonal and affinity-purified antibodies against small molecules, hormones and proteins, plus secondary antibodies and related immunoreagents for assay development.
Pre-made conjugates
Pre-prepared protein and hapten conjugates (multiple carrier and enzyme options) for immunogen preparation, assay standards and detection reagents.
Affinity resins
Functionalized chromatography resins for capture or analytical workflows supplied in research-scale and larger volumes.
Chromogenic and chemiluminescent substrates
Reagents for enzyme-based detection (peroxidase and alkaline phosphatase) formulated for ELISA, Western blot and membrane assays with options for single-bottle ready-to-use formats and two-component systems.
Cyclodextrins and derivatives
Native and modified alpha, beta and gamma cyclodextrins and derivatives for solubility enhancement, inclusion complexation and formulation use; supplied with analytical data and flexible packaging sizes.
Fluorescent dyes and reactive labels
High-purity fluorescent compounds and reactive esters for labeling proteins, peptides and nucleic acids used in imaging and assay development.
Antibodies and immunoreagents
Polyclonal and affinity-purified antibodies against small molecules, hormones and proteins, plus secondary antibodies and related immunoreagents for assay development.
Pre-made conjugates
Pre-prepared protein and hapten conjugates (multiple carrier and enzyme options) for immunogen preparation, assay standards and detection reagents.
Affinity resins
Functionalized chromatography resins for capture or analytical workflows supplied in research-scale and larger volumes.
Services
Hapten–protein coupling and enzyme/biotin conjugations with controlled coupling ratios for immunogen and assay reagent production.
Polyclonal antibody generation in common host species with affinity purification and characterization.
Custom peptide synthesis services offering peptides up to ~50 amino acids and >95% purity specifications.
Tailored chemical modification of cyclodextrins (sulfation, phosphation, hydroxypropylation and other patterns) with defined degree-of-substitution and analytical characterization.
Reactive dye labeling of proteins and peptides using amine-reactive chemistries and other fluorophore conjugation options.
Hapten–protein coupling and enzyme/biotin conjugations with controlled coupling ratios for immunogen and assay reagent production.
Polyclonal antibody generation in common host species with affinity purification and characterization.
Custom peptide synthesis services offering peptides up to ~50 amino acids and >95% purity specifications.
Tailored chemical modification of cyclodextrins (sulfation, phosphation, hydroxypropylation and other patterns) with defined degree-of-substitution and analytical characterization.
Reactive dye labeling of proteins and peptides using amine-reactive chemistries and other fluorophore conjugation options.
Expertise Areas
- Diagnostic reagent formulation and manufacturing
- Chemiluminescent and chromogenic detection chemistry
- Cyclodextrin excipient synthesis and modification
- Custom conjugation and peptide synthesis
Key Technologies
- Chemiluminescent substrate chemistry
- Chromogenic substrate chemistry (TMB and alternatives)
- Enzyme-specific substrate formulations (AP, glucuronidase, beta-galactosidase)
- Cyclodextrin chemistry and derivative synthesis
News & Updates
Technical guide comparing TMB and other HRP substrates, single-bottle vs two-bottle systems, and best practices for plate-based ELISA workflows.
Comparative guide on structural differences, solubility and applications of alpha, beta and gamma cyclodextrins.
Hydroxypropyl Beta Cyclodextrin (HPBCD): The Gold Standard Excipient for Drug Solubility Enhancement
Overview of hydroxypropyl-beta-cyclodextrin properties, applications in parenteral and ophthalmic formulations, regulatory considerations and supplier selection factors.
Manufacturing follows ISO 13485 quality management standards and company provides CE marking and selected FDA registrations for diagnostic-use products.
Operating a US-based manufacturing facility since 1998 with global distribution to research and diagnostic customers.
Supplies products to customers in multiple countries with domestic shipping and export support.
Technical guide comparing TMB and other HRP substrates, single-bottle vs two-bottle systems, and best practices for plate-based ELISA workflows.
Comparative guide on structural differences, solubility and applications of alpha, beta and gamma cyclodextrins.
Hydroxypropyl Beta Cyclodextrin (HPBCD): The Gold Standard Excipient for Drug Solubility Enhancement
Overview of hydroxypropyl-beta-cyclodextrin properties, applications in parenteral and ophthalmic formulations, regulatory considerations and supplier selection factors.
Manufacturing follows ISO 13485 quality management standards and company provides CE marking and selected FDA registrations for diagnostic-use products.
Operating a US-based manufacturing facility since 1998 with global distribution to research and diagnostic customers.
Supplies products to customers in multiple countries with domestic shipping and export support.