Sandia Biotech


Supplier and developer of fluorescent-protein–based research reagents and assay kits. Offers intrinsically fluorescent recombinant antibody derivatives, split fluorescent-protein complementation assays and detection reagents, protein-based protease activity biosensor kits, expression plasmids and controls, and proprietary small-molecule modulators of the G protein-coupled estrogen receptor (GPER). Products are marketed for research use only. The company operates an online catalog and provides custom reagent development and manufacturing scale-up services.

Industries

Biotechnology
Life Science
Product Research
Wellness
Biotechnology Research

Nr. of Employees

small (1-50)

Sandia Biotech

Albuquerque, New Mexico, United States


Patents

Systematic creation of fluorescent fusion polypeptides

US-11702766-B2

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Products

Bacterial split fluorescent-protein solubility assay kit

In vitro bacterial split fluorescent-protein assay kit for assessing protein folding and solubility using split-protein complementation.

Mammalian split-protein S11 expression plasmid

Plasmid for expression of a split fluorescent-protein fragment in mammalian cells for complementation assays.

Bacterial split-protein S11 expression plasmid

Plasmid for expression of a split fluorescent-protein fragment in bacterial systems.

Multispectral detection reagents (cyan/green/yellow variants)

Detection reagents in multiple fluorescent-protein spectral variants for split-protein complementation workflows and multicolor imaging.

Expression plasmid for robust folding fluorescent protein variants

Expression plasmid for a fluorescent protein variant designed for improved folding and fluorescence stability (robust/folding-enhanced variants).

Split-protein positive-control construct

Prepared positive-control protein construct for validating split-protein complementation assays and troubleshooting.

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Services

Custom design and production of intrinsically fluorescent antibody-fragment probes for imaging and assay applications.

Process development and licensing support to scale production of intrinsically fluorescent recombinant antibody derivatives and related reagent kits for partners or larger-volume supply.

Expertise Areas

  • Fluorescent reagent development
  • Split fluorescent-protein complementation assays
  • Recombinant fluorescent antibody (scFv–FP) engineering
  • Protease activity biosensor development
  • Show More (4)

Key Technologies

  • Split fluorescent-protein complementation
  • scFv–fluorescent protein genetic fusions
  • Protein-based fluorescent protease reporters
  • Expression plasmid vectors for bacterial and mammalian expression
  • Show More (4)

News & Updates

Publication demonstrating use of split fluorescent-protein complementation to determine topology of endoplasmic reticulum-associated cellular and viral proteins.

Recorded webinar covering split-protein complementation and folding-enhanced fluorescent protein variants for protein folding and solubility assays.

Attendance with the New Mexico Pavilion to showcase recombinant fluorescent affinity reagent technology and microscopy integration.

Company licensed a recombinant intrinsically fluorescent antibody platform to develop a panel of recombinant fluorescent antibody derivatives and advanced it into a scalable manufacturing process.


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