La Jolla Institute for Allergy & Immunology
Nonprofit research institute focused on human immunology and translational research. Core activities include mechanistic studies of T and B cell responses, epitope identification, antibody discovery and structural analysis, vaccine and adjuvant evaluation, allergy and flavivirus research, single-cell and bulk transcriptomics, shared research cores (flow cytometry, sequencing, microscopy, cryo-EM), database and bioinformatics platform development, and coordination of clinical and observational studies.
Industries
Nr. of Employees
large (251-1000)
La Jolla Institute for Allergy & Immunology
Products
Database of Immune Cell Epigenomics (DICE)
Open-access database for immune cell epigenomic and gene-expression data to support analysis of how gene regulation drives immune function.
Immunology and epitope mapping databases
Publicly accessible immunology databases and tools for epitope mapping, epitope analysis and immunogenomics to support target selection and computational analyses.
Allergy and flavivirus research projects
Active research projects in allergen epitope identification, peptide-based immunotherapy concepts, and flavivirus vaccine and pathogenesis studies.
Database of Immune Cell Epigenomics (DICE)
Open-access database for immune cell epigenomic and gene-expression data to support analysis of how gene regulation drives immune function.
Immunology and epitope mapping databases
Publicly accessible immunology databases and tools for epitope mapping, epitope analysis and immunogenomics to support target selection and computational analyses.
Allergy and flavivirus research projects
Active research projects in allergen epitope identification, peptide-based immunotherapy concepts, and flavivirus vaccine and pathogenesis studies.
Services
Core sequencing services
Next-generation sequencing and sequencing support for genomics and single-cell projects.
Flow cytometry and cell sorting core
Multi-parameter cytometry and cell sorting services with expert consultation.
Microscopy & histology services
Tissue processing, histological staining and microscopy imaging support.
Cryo-EM imaging services
Access to cryo-electron microscopy and structural imaging pipelines.
Clinical studies coordination
Recruitment, sample collection and longitudinal study support via an institutional clinical investigation center.
Core sequencing services
Next-generation sequencing and sequencing support for genomics and single-cell projects.
Flow cytometry and cell sorting core
Multi-parameter cytometry and cell sorting services with expert consultation.
Microscopy & histology services
Tissue processing, histological staining and microscopy imaging support.
Cryo-EM imaging services
Access to cryo-electron microscopy and structural imaging pipelines.
Clinical studies coordination
Recruitment, sample collection and longitudinal study support via an institutional clinical investigation center.
Expertise Areas
- Human immunology and adaptive immune responses
- Epitope identification and immunogen design
- Vaccine research and translational vaccine design
- Adjuvant evaluation in preclinical models
Key Technologies
- Next-generation sequencing (NGS)
- Single-cell RNA sequencing
- Bulk RNA-seq / transcriptomics
- Spatial transcriptomics