Member
2 Awards

Centivax


Centivax is a universal immunity company, deploying a proprietary computational immune-engineering platform to create vaccines and therapies that deliver universal protection against entire classes of diverse targets. The lead clinical candidate for influenza—featured in The New Yorker, the Netflix docuseries Pandemic: How to Prevent an Outbreak, and other outlets—addresses a greater than $7 billion global flu market, with follow-on programs spanning a growing pipeline for RSV/hMPV, herpesviruses, HIV, malaria, oncology, and a universal antivenom. This growing portfolio underscores the technology's broad potential not only to protect against a wide array of infectious diseases–including viral, bacterial, protozoan, fungal, parasitic and man-made bioterror threats–but also to improve healthspan by reducing the long-term complications these pathogens can trigger, such as cancer, autoimmune conditions, cardiovascular and neurodegenerative disease. Centivax is headquartered in South San Francisco, California. Visit www.centivax.com and follow @Centivax on X.

Industries

biotechnology
health-care
health-diagnostics
medical

Nr. of Employees

small (1-50)

Centivax

1 Tower Place, Suite 800, South San Francisco, CA 94080

Awards

Rapid development of an optimized antibody for treatment of COVID-19

Funding (ceiling)

$1,206,824

Award Year

2020

Military Infectious Disease - Prototype Innovation Program (MID-PIP)

Generation of high affinity monoclonal antibodies to Staphylococcus sp. and Pseudomonas sp. for the prevention and treatment of bacterial wound infections and sepsis.

Funding (ceiling)

$1,839,259

Award Year

2020


Patents

Epitope focusing by variable effective antigen surface concentration

2024-07-23 • US-12043647-B2

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Epitope focusing by variable effective antigen surface concentration

2023-01-24 • US-11560409-B2

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Anti-SARS-Cov-2 antibodies derived from 6nb6

2021-07-06 • US-11053304-B1

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Anti-SARS-Cov-2 antibodies derived from CR3022

2021-06-15 • US-11034762-B1

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Anti-SARS-Cov-2 antibodies derived from 3bgf

2021-06-08 • US-11028167-B1

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Anti-SARS-CoV-2 antibodies derived from 2DD8

2021-06-08 • US-11028150-B1

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Products

Universal (broad-spectrum) influenza vaccine (preclinical)

A vaccine program designed to generate immunity against conserved influenza epitopes; completed preclinical studies in multiple animal species and human immune organoids, with plans for clinical testing.

Broad-spectrum antibody therapeutics (programs)

Pipeline of broadly neutralizing antibody programs including anti-infectives, anti-wound pathogen antibodies, and antivenom antibody programs derived from human repertoires.

Broad-spectrum injectable for COVID-19 (clinical development partnership)

A broad-spectrum antibody injectable program for SARS-CoV-2 advanced into strategic partnerships to initiate clinical development with external research centers and funding support.

Expertise Areas

  • Broad-spectrum vaccine development
  • Antibody discovery and engineering
  • Computational immunology and machine learning
  • Preclinical animal models and in vivo evaluation
  • Show More (6)

Key Technologies

  • Epitope-focused immunogen design
  • Next-generation sequencing (immune repertoire sequencing)
  • Single-cell receptor sequencing
  • Machine learning for antibody engineering
  • Show More (6)

Key People

Jacob Glanville

Chief Executive Officer

LinkedIn

Sawsan Youssef

Chief Science Officer

Nicholas Bayless

Chief Medical Officer

David Tsao

Chief Business Officer

Stephanie Wisner

Chief Operating Officer

Jerald Sadoff

Chief Technology Officer

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Featured In Technology Showcase

Centivax’s Novel Engineered Antibody Neutralizes Pandemic Coronaviruses and has been Engineered for Enhanced Therapeutic Properties

With support from MTEC, Centivax has rapidly developed a potent antibody therapeutic for COVID-19 in under nine weeks. Engineered for safety, stability, and field deployment, the treatment has completed preclinical studies and is advancing toward clinical trials to address both military and civilian healthcare needs.


News & Updates

An article discussing Centivax's efforts to combat COVID-19 variants through antibody development.

Centivax CEO emphasizes the importance of widespread vaccination to prevent COVID-19 mutations.

Discussion on strategies to combat COVID-19 amidst the emergence of the Omicron variant.

An article exploring the shift in focus towards COVID-19 therapeutics by a prominent figure from the Netflix docuseries.

Highlighting Stephanie Wisner's recognition in Forbes 30 Under 30 for her contributions to Centivax.


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