Centivax
Centivax is a universal immunity company, deploying a proprietary computational immune-engineering platform to create vaccines and therapies that deliver universal protection against entire classes of diverse targets. The lead clinical candidate for influenza—featured in The New Yorker, the Netflix docuseries Pandemic: How to Prevent an Outbreak, and other outlets—addresses a greater than $7 billion global flu market, with follow-on programs spanning a growing pipeline for RSV/hMPV, herpesviruses, HIV, malaria, oncology, and a universal antivenom. This growing portfolio underscores the technology's broad potential not only to protect against a wide array of infectious diseases–including viral, bacterial, protozoan, fungal, parasitic and man-made bioterror threats–but also to improve healthspan by reducing the long-term complications these pathogens can trigger, such as cancer, autoimmune conditions, cardiovascular and neurodegenerative disease. Centivax is headquartered in South San Francisco, California. Visit www.centivax.com and follow @Centivax on X.
Industries
Nr. of Employees
small (1-50)
Centivax
1 Tower Place, Suite 800, South San Francisco, CA 94080
Awards
Rapid development of an optimized antibody for treatment of COVID-19
Funding (ceiling)
$1,206,824
Award Year
2020
Military Infectious Disease - Prototype Innovation Program (MID-PIP)
Generation of high affinity monoclonal antibodies to Staphylococcus sp. and Pseudomonas sp. for the prevention and treatment of bacterial wound infections and sepsis.
Funding (ceiling)
$1,839,259
Award Year
2020
Patents
Epitope focusing by variable effective antigen surface concentration
2024-07-23 • US-12043647-B2
View DetailsEpitope focusing by variable effective antigen surface concentration
2023-01-24 • US-11560409-B2
View Details
Epitope focusing by variable effective antigen surface concentration
2024-07-23 • US-12043647-B2
View DetailsEpitope focusing by variable effective antigen surface concentration
2023-01-24 • US-11560409-B2
View DetailsProducts
Universal (broad-spectrum) influenza vaccine (preclinical)
A vaccine program designed to generate immunity against conserved influenza epitopes; completed preclinical studies in multiple animal species and human immune organoids, with plans for clinical testing.
Broad-spectrum antibody therapeutics (programs)
Pipeline of broadly neutralizing antibody programs including anti-infectives, anti-wound pathogen antibodies, and antivenom antibody programs derived from human repertoires.
Broad-spectrum injectable for COVID-19 (clinical development partnership)
A broad-spectrum antibody injectable program for SARS-CoV-2 advanced into strategic partnerships to initiate clinical development with external research centers and funding support.
Universal (broad-spectrum) influenza vaccine (preclinical)
A vaccine program designed to generate immunity against conserved influenza epitopes; completed preclinical studies in multiple animal species and human immune organoids, with plans for clinical testing.
Broad-spectrum antibody therapeutics (programs)
Pipeline of broadly neutralizing antibody programs including anti-infectives, anti-wound pathogen antibodies, and antivenom antibody programs derived from human repertoires.
Broad-spectrum injectable for COVID-19 (clinical development partnership)
A broad-spectrum antibody injectable program for SARS-CoV-2 advanced into strategic partnerships to initiate clinical development with external research centers and funding support.
Expertise Areas
- Broad-spectrum vaccine development
- Antibody discovery and engineering
- Computational immunology and machine learning
- Preclinical animal models and in vivo evaluation
Key Technologies
- Epitope-focused immunogen design
- Next-generation sequencing (immune repertoire sequencing)
- Single-cell receptor sequencing
- Machine learning for antibody engineering
Key People
Sawsan Youssef
Chief Science Officer
Nicholas Bayless
Chief Medical Officer
David Tsao
Chief Business Officer
Stephanie Wisner
Chief Operating Officer
Jerald Sadoff
Chief Technology Officer
Sawsan Youssef
Chief Science Officer
Nicholas Bayless
Chief Medical Officer
David Tsao
Chief Business Officer
Stephanie Wisner
Chief Operating Officer
Jerald Sadoff
Chief Technology Officer
Featured In Technology Showcase
Centivax’s Novel Engineered Antibody Neutralizes Pandemic Coronaviruses and has been Engineered for Enhanced Therapeutic Properties
With support from MTEC, Centivax has rapidly developed a potent antibody therapeutic for COVID-19 in under nine weeks. Engineered for safety, stability, and field deployment, the treatment has completed preclinical studies and is advancing toward clinical trials to address both military and civilian healthcare needs.
News & Updates
An article discussing Centivax's efforts to combat COVID-19 variants through antibody development.
Centivax CEO emphasizes the importance of widespread vaccination to prevent COVID-19 mutations.
Discussion on strategies to combat COVID-19 amidst the emergence of the Omicron variant.
An article exploring the shift in focus towards COVID-19 therapeutics by a prominent figure from the Netflix docuseries.
Highlighting Stephanie Wisner's recognition in Forbes 30 Under 30 for her contributions to Centivax.
An article discussing Centivax's efforts to combat COVID-19 variants through antibody development.
Centivax CEO emphasizes the importance of widespread vaccination to prevent COVID-19 mutations.
Discussion on strategies to combat COVID-19 amidst the emergence of the Omicron variant.
An article exploring the shift in focus towards COVID-19 therapeutics by a prominent figure from the Netflix docuseries.
Highlighting Stephanie Wisner's recognition in Forbes 30 Under 30 for her contributions to Centivax.