The Wistar Institute


The Wistar Institute is a global leader in biomedical research, focusing on cancer, immunology, infectious diseases, and vaccine development. It aims to solve challenging health problems through innovative research, collaboration, and education, translating discoveries into therapies and vaccines to improve human health.

Industries

biotechnology
medical

Nr. of Employees

large (251-1000)

The Wistar Institute

3601 Spruce Street, Philadelphia, PA 19104


Patents

Vaccines against Nipah virus, and methods of using same

US-12357683-B2

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Variant survivin vaccine for treatment of myeloma

US-12344642-B2

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Use of lactoferrin for generating myeloid-derived suppressor cells

US-12295990-B2

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DNA vaccine against crimean-congo hemorrhagic fever virus (CCHFV)

US-12296001-B2

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Adenoviral vectors encoding hepatitis b viral antigens fused to herpes virus glycoprotein d and methods of using the same

US-12290561-B2

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Acetyl-CoA synthetase 2 (ACSS2) inhibitors and methods using same

US-12281084-B2

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Products

Nucleic-acid vaccine candidates (research-stage)

Research-stage DNA-based vaccine constructs developed and evaluated in preclinical models, with at least one candidate advanced to Phase I clinical testing.

Monoclonal antibody constructs (research-stage)

Engineered monoclonal antibody constructs developed for antiviral and immuno-oncology applications using DNA-encoded and recombinant approaches.


Services

Sequencing and genomics workflows for research projects, with data generation and support for downstream analysis.

Multiparameter flow cytometry and cell sorting services including experimental setup and data analysis support.

Microscopy instrumentation and image analysis support for cellular and tissue imaging experiments.

Mass-spectrometry-based proteome and metabolome profiling, sample processing and data analysis.

High-throughput screening and recombinant protein expression to support target discovery and assay development.

Tissue processing, embedding, sectioning and staining to support histological analysis.

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Expertise Areas

  • Vaccine development
  • Immunotherapy and immuno-oncology
  • Cancer basic and translational research
  • HIV cure and viral diseases research
  • Show More (9)

Key Technologies

  • Nucleic-acid (DNA) vaccine platforms
  • Synthetic nucleic-acid technology
  • Monoclonal antibody engineering
  • Next-generation sequencing (NGS)
  • Show More (9)

News & Updates

The Wistar Institute commemorated the milestone expansion and opening of its HIV Cure and Viral Diseases Center.

Dr. Jesper Pallesen uses cryo-electron microscopy to view protein structures at the atomic level.

Dr. Ian Tietjen, education director, discusses his return to Africa and global health initiatives.

Announcement of Joshua Friedman joining the Wistar Board of Trustees.

Research by Wistar scientists on viral immune evasion mechanisms.

First independent biomedical research institute in the U.S.

Founded in 1892, Wistar was the first independent biomedical research institute in the United States.

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