Incisive Genetics


Incisive Genetics Inc. is a Canadian biotech company dedicated to developing innovative gene delivery platforms for genetic therapies. Their mission is to address the critical challenge of effective and safe delivery of gene editing machinery into target tissues, aiming to create potentially curative therapies for serious genetic diseases. They focus on their proprietary Incisive Delivery System™ and OmniaTM platform, which are non-viral delivery methods for CRISPR-based gene therapies, enabling precise, efficient, and safe gene editing solutions.

Industries

biotechnology
genetics
health-care
medical-device

Nr. of Employees

small (1-50)

Incisive Genetics

Vancouver, British Columbia, Canada, North America


Products

Patent-pending non-viral LNP delivery platform for CRISPR RNPs

A lipid nanoparticle-based delivery platform designed to encapsulate and deliver pre-formed CRISPR protein–guide RNA complexes (RNPs) for in vivo genome editing applications.

Preclinical CRISPR-based therapeutic candidates

Therapeutic development efforts that pair the LNP delivery platform with active endonuclease proteins and target-specific guide RNAs to create candidate treatments for genetic diseases.


Services

In-house platform R&D and preclinical development

Internal research and development of a non-viral LNP delivery platform and conduct of preclinical studies to generate proof-of-concept gene editing data.

Expertise Areas

  • Gene delivery platform development
  • Lipid nanoparticle formulation for in vivo use
  • CRISPR ribonucleoprotein (RNP) delivery
  • Preclinical in vivo gene editing studies
  • Show More (4)

Key Technologies

  • Lipid nanoparticles (LNPs)
  • CRISPR ribonucleoprotein (RNP) delivery
  • Guide RNA-based targeting
  • Endonuclease protein delivery
  • Show More (4)

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