HeartWorks
HeartWorks is a nonprofit organization dedicated to transforming the future for children born with congenital heart defects (CHD). They build, test, and deliver innovative therapies to cure CHD, empowering families to lead full, enriching lives. Their mission is to find cures for congenital heart defects and change lives, with a vision of a future where people with CHD thrive with lasting health and longevity.
Industries
Nr. of Employees
small (1-50)
HeartWorks
Patents
Products
Bioengineered cardiac tissue (autologous cardiac-lineage cells)
Autologous cells differentiated to cardiac lineage and formed into contracting tissue intended for delivery into the heart to strengthen myocardial function; currently evaluated in Phase I feasibility/safety studies.
Cardiac spheroids for catheter delivery
Three-dimensional spheroid constructs composed of heart cells designed for catheter-mediated delivery to coronary arteries to improve cell survival and engraftment.
Bioengineered cardiac tissue (autologous cardiac-lineage cells)
Autologous cells differentiated to cardiac lineage and formed into contracting tissue intended for delivery into the heart to strengthen myocardial function; currently evaluated in Phase I feasibility/safety studies.
Cardiac spheroids for catheter delivery
Three-dimensional spheroid constructs composed of heart cells designed for catheter-mediated delivery to coronary arteries to improve cell survival and engraftment.
Services
Membership-based clinical data cooperative that collects medical journey data from individuals with congenital heart defects to inform research and accelerate trial recruitment.
Collection of small skin biopsy samples from consenting adults with CHD to generate autologous cells for downstream clinical-grade manufacturing.
Sponsorship and operational coordination of interventional clinical trials, including first-in-human Phase I studies of bioengineered cardiac tissue.
Structured 60-minute virtual tours of laboratory processes to demonstrate the workflow from skin biopsy to beating cardiac tissue and engage families, donors, and collaborators.
Clinical-grade cell culture processing and expansion workflows designed to produce materials intended for investigational human use.
Membership-based clinical data cooperative that collects medical journey data from individuals with congenital heart defects to inform research and accelerate trial recruitment.
Collection of small skin biopsy samples from consenting adults with CHD to generate autologous cells for downstream clinical-grade manufacturing.
Sponsorship and operational coordination of interventional clinical trials, including first-in-human Phase I studies of bioengineered cardiac tissue.
Structured 60-minute virtual tours of laboratory processes to demonstrate the workflow from skin biopsy to beating cardiac tissue and engage families, donors, and collaborators.
Clinical-grade cell culture processing and expansion workflows designed to produce materials intended for investigational human use.
Expertise Areas
- Cell-based cardiac therapy development
- Clinical trial management and sponsorship
- GMP clinical-grade cell manufacturing
- Patient registry and data cooperative management
Key Technologies
- Induced pluripotent stem cell (iPSC) generation
- Cardiac lineage differentiation
- Bioengineered contracting cardiac tissue
- Cardiac spheroids
News & Updates
This annual, free event dedicated to connection, education, and fun for the whole family. It explores the future of single ventricle heart defects through inspiring conversations, groundbreaking science, and hands-on experiences. Attendees can hear from Levi’s mom, Lauren, share stories, learn about research and clinical trials, and discover how HeartWorks is building hearts and advancing care.
This annual, free event dedicated to connection, education, and fun for the whole family. It explores the future of single ventricle heart defects through inspiring conversations, groundbreaking science, and hands-on experiences. Attendees can hear from Levi’s mom, Lauren, share stories, learn about research and clinical trials, and discover how HeartWorks is building hearts and advancing care.