Heartseed


Heartseed is dedicated to transforming the treatment of severe heart failure through innovative regenerative medicine. Founded in 2015, the company focuses on developing therapies using iPS cells to generate cardiomyocytes for transplantation, aiming to open new doors in cardiovascular disease treatment worldwide.

Industries

beauty
biotechnology
health-care
medical
nursing-and-residential-care

Nr. of Employees

small (1-50)

Heartseed

Seavans South Building 5F, 1-2-3 Shibaura, Minato-ku, Tokyo 105-0023, JAPAN


Patents

Method of constructing masses of myocardial cells and use of the myocardial cell mass

US-10918671-B2

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Method for producing high-quality iPS cells

US-10544396-B2

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Method for producing induced pluripotent stem cells

US-9447432-B2

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Method for purifying cardiomyocytes or programmed cardiomyocytes derived from stem cells or fetuses

US-9115342-B2

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Method of constructing masses of myocardial cells and use of the myocardial cell mass

US-9109205-B2

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Products

HS-001 (investigational allogeneic iPSC-derived cardiomyocyte therapy)

An investigational allogeneic iPSC-derived cardiomyocyte product developed for transplantation into failing myocardium to restore contractile function in patients with heart failure with reduced ejection fraction.


Services

Organizing and conducting early-phase clinical studies of iPSC-derived cardiomyocyte therapeutics, including protocol implementation and patient enrollment.

Joint research with external partners to develop more convenient intramyocardial delivery methods and more efficient iPSC production processes.

Expertise Areas

  • Cardiac regenerative medicine
  • iPSC-derived cell therapy development
  • Preclinical and early-phase clinical development
  • CMC and GMP manufacturing planning for biologics
  • Show More (4)

Key Technologies

  • Induced pluripotent stem cell (iPSC) differentiation
  • Cardiomyocyte spheroid (microtissue) fabrication
  • Cell purification and differentiation processes
  • Intramyocardial injection delivery
  • Show More (3)

News & Updates

Heartseed was featured on CNN’s 'Tomorrow Transformed' on October 8, 2024.

Heartseed was featured on NHK World's CATCH JAPAN on July 19, 2021.

A feature on stem cell innovations including Heartseed, published on July 19, 2021.

A feature on stem cell innovations including Heartseed.

Recognition for Heartseed as Healthcare Company of the Year 2020.

Interview with CEO Keiichi Fukuda on BS Fuji.

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