Fina Biosolutions
Fina Biosolutions LLC was founded in 2006 by Dr. Andrew Lees with a focus on helping emerging market vaccine manufacturers learn to make affordable conjugate vaccines. The company offers bioconjugation and protein services, and is located in Maryland’s biotechnology corridor. It specializes in conjugation chemistry, bioconjugation, and conjugate vaccines, providing laboratory and consulting services globally.
Industries
Nr. of Employees
small (1-50)
Fina Biosolutions
Rockville, Maryland, United States, North America
Products
Recombinant diphtheria-derived carrier protein for conjugation
Recombinant diphtheria-derived carrier protein produced for preclinical use and available in GMP-grade material for clinical applications as a carrier in conjugate vaccines.
Functionalized carrier proteins with conjugation handles
Carrier proteins chemically modified to present reactive groups (maleimide, azide, bromoacetate or click-compatible handles) to simplify and enable site-selective conjugation workflows.
Toxoid-derived and recombinant tetanus carrier materials
Toxoid-derived carrier proteins and recombinant tetanus-derived constructs offered in native and functionalized forms for conjugation applications.
Functionalized dextran polymers
A range of dextran polymers with tailored functional groups and labeling for conjugation, assay development and imaging, including fluorescent and high-substitution maleimide variants.
Antibody-dextran conjugates (including anti-Ig reagents)
Pre-made or custom antibody-dextran conjugates for use as detection reagents, assay activators and B-cell activation tools; offerings include anti-IgD and anti-IgM formats in mouse and human variants.
Streptavidin-dextran conjugates
Streptavidin conjugated to dextran backbones for biotin-based capture and detection, offered in fluorescent and non-fluorescent forms.
Recombinant diphtheria-derived carrier protein for conjugation
Recombinant diphtheria-derived carrier protein produced for preclinical use and available in GMP-grade material for clinical applications as a carrier in conjugate vaccines.
Functionalized carrier proteins with conjugation handles
Carrier proteins chemically modified to present reactive groups (maleimide, azide, bromoacetate or click-compatible handles) to simplify and enable site-selective conjugation workflows.
Toxoid-derived and recombinant tetanus carrier materials
Toxoid-derived carrier proteins and recombinant tetanus-derived constructs offered in native and functionalized forms for conjugation applications.
Functionalized dextran polymers
A range of dextran polymers with tailored functional groups and labeling for conjugation, assay development and imaging, including fluorescent and high-substitution maleimide variants.
Antibody-dextran conjugates (including anti-Ig reagents)
Pre-made or custom antibody-dextran conjugates for use as detection reagents, assay activators and B-cell activation tools; offerings include anti-IgD and anti-IgM formats in mouse and human variants.
Streptavidin-dextran conjugates
Streptavidin conjugated to dextran backbones for biotin-based capture and detection, offered in fluorescent and non-fluorescent forms.
Services
Conjugation services
Contract conjugation of polysaccharides, dextrans and other haptens to carrier proteins and reagents for research and vaccine development.
CDAP conjugation training program
Training and hands-on instruction for CDAP-based polysaccharide-protein conjugation and technology transfer to client labs.
Protein expression and purification
Contract expression and downstream purification of recombinant proteins using bacterial expression systems.
Analytical services (MALS, moisture, polymer analysis)
Analytical testing including multi-angle light scattering, moisture analysis and polymer sizing to support characterization and comparability.
Immunoassay design and antibody reagents
Design of immunoassays and supply/development of antibody reagents, including labeled and biotinylated antibodies and custom monoclonal reagents.
Technical resources and white papers
Provision of technical white papers, application notes and downloadable resources describing conjugation methods and reagent applications.
Conjugation services
Contract conjugation of polysaccharides, dextrans and other haptens to carrier proteins and reagents for research and vaccine development.
CDAP conjugation training program
Training and hands-on instruction for CDAP-based polysaccharide-protein conjugation and technology transfer to client labs.
Protein expression and purification
Contract expression and downstream purification of recombinant proteins using bacterial expression systems.
Analytical services (MALS, moisture, polymer analysis)
Analytical testing including multi-angle light scattering, moisture analysis and polymer sizing to support characterization and comparability.
Immunoassay design and antibody reagents
Design of immunoassays and supply/development of antibody reagents, including labeled and biotinylated antibodies and custom monoclonal reagents.
Technical resources and white papers
Provision of technical white papers, application notes and downloadable resources describing conjugation methods and reagent applications.
Expertise Areas
- Bioconjugation and conjugate vaccine development
- Recombinant carrier protein production and GMP supply
- Functionalized polysaccharide (dextran) synthesis and modification
- Analytical characterization and comparability testing
Key Technologies
- CDAP-based polysaccharide-to-protein conjugation
- Protein functionalization chemistries (maleimide, azide, bromoacetate, click-compatible)
- Recombinant protein expression in E. coli
- Multi-angle light scattering (MALS)