ExThera Medical Corporation


ExThera Medical develops and commercializes extracorporeal blood filtration devices, including the Seraph 100 Microbind Affinity Blood Filter and ONCObind, for removing harmful substances from the bloodstream. The company aims to serve healthcare professionals and patients worldwide, with a focus on treating severe infections, sepsis, COVID-19, and metastatic cancer. Their products have demonstrated life-saving capabilities and are involved in clinical trials and regulatory processes to expand their indications.

Industries

biotechnology
health-care
medical
medical-device

Nr. of Employees

small (1-50)

ExThera Medical Corporation

757 Arnold Drive, Suite B, Martinez, California 94553


Patents

Methods for removing cytokines from blood with surface immobilized polysaccharides

US-11123466-B2

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Methods for removing cytokines from blood with surface immobilized polysaccharides

US-10086126-B2

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Methods for removing cytokines from blood with surface immobilized polysaccharides

US-9408962-B2

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Method for removing cytokines from blood with surface immobilized polysaccharides

US-8758286-B2

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Products

Affinity-based hemoperfusion blood filter

Disposable extracorporeal blood filter employing affinity adsorption media to bind and remove pathogens, circulating tumor cells and sepsis mediators from whole blood during extracorporeal circulation.

Oncology-focused hemoperfusion procedure (investigational)

Investigational extracorporeal hemoperfusion procedure using affinity adsorption media to capture and reduce circulating tumor cells as an adjunct to cancer therapy; studied under feasibility and investigational device protocols.


Services

Design, sponsorship and operational support for randomized controlled trials, observational registries and feasibility studies evaluating extracorporeal blood purification therapies.

Establishment of regional distribution and co-marketing agreements to enable device supply and clinical adoption in target markets.

Expertise Areas

  • Extracorporeal blood purification
  • Sepsis and bloodstream infection management
  • Adjunctive oncology approaches targeting circulating tumor cells
  • Clinical trial design and multicenter trial operations
  • Show More (4)

Key Technologies

  • Hemoperfusion / extracorporeal blood purification
  • Affinity adsorption microbeads with immobilized heparin
  • Hemoadsorption media for pathogen and circulating tumor cell capture
  • Integration with extracorporeal circuits (dialysis, ECMO)
  • Show More (1)

News & Updates

A study published in Nature's Scientific Reports found that the Seraph 100 blood filter significantly reduced pathogen load in septic patients following cardiac surgery, leading to faster recovery and lower incidence of kidney injury.

Research demonstrated the potential of Seraph 100 to remove circulating tumor cells, which may help in reducing metastasis and improving survival in pancreatic cancer.

The company was awarded for its innovative approach to treating sepsis with blood filtration technology.

The trial demonstrated the safety and initial signals of efficacy of the ONCObind device in removing circulating tumor cells in pancreatic cancer patients.

The company is conducting a clinical trial to evaluate the efficacy of the ONCObind device in removing circulating tumor cells from blood, potentially reducing metastasis and improving survival.

The Seraph 100 device has been authorized by the FDA under EUA for the treatment of COVID-19, marking a significant regulatory milestone.

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