VitaCyte
VitaCyte specializes in the manufacture and supply of GMP Grade purified-defined collagenase and protease enzymes for cell and tissue dissociation. The company is dedicated to supporting researchers, commercial cell suppliers, and institutions involved in cell therapy and transplantation, providing high-quality products that enhance the efficiency and effectiveness of cell isolation processes. VitaCyte is committed to improving the science of cell recovery and has a history of innovative solutions in the field of cell isolation, contributing to significant advancements such as the Edmonton Protocol for islet transplantation. Their products, particularly the purified-defined collagenase, ensure high lot-to-lot consistency and rigorous enzyme characterization, setting a standard in the industry.
Industries
Nr. of Employees
small (1-50)
VitaCyte
Products
Lyophilized purified collagenase preparations
Lyophilized purified collagenase preparations with defined composition and specified collagen degradation activity intended for tissue dissociation and cell isolation workflows.
Purified neutral protease preparations
Neutral protease enzyme preparations provided with activity specifications to supplement collagenase in tissue dissociation formulations, with non-animal and GMP-grade options.
Application-specific pre-blended enzyme mixtures
Pre-formulated enzyme mixtures optimized for specific applications (rodent islet isolation, adipose SVF isolation, human islet/hepatocyte workflows) with recommended dosing and method guidance.
Defined collagenase–protease mixtures for general tissue dissociation
Defined mixtures with fixed neutral protease activity and selectable collagenase activity bands for broad tissue dissociation uses and for transitioning from traditional crude collagenase products.
Lyophilized purified collagenase preparations
Lyophilized purified collagenase preparations with defined composition and specified collagen degradation activity intended for tissue dissociation and cell isolation workflows.
Purified neutral protease preparations
Neutral protease enzyme preparations provided with activity specifications to supplement collagenase in tissue dissociation formulations, with non-animal and GMP-grade options.
Application-specific pre-blended enzyme mixtures
Pre-formulated enzyme mixtures optimized for specific applications (rodent islet isolation, adipose SVF isolation, human islet/hepatocyte workflows) with recommended dosing and method guidance.
Defined collagenase–protease mixtures for general tissue dissociation
Defined mixtures with fixed neutral protease activity and selectable collagenase activity bands for broad tissue dissociation uses and for transitioning from traditional crude collagenase products.
Expertise Areas
- Tissue-dissociation enzyme manufacturing
- Ancillary material supply and regulatory documentation for cell therapies
- Cell isolation protocol development and optimization
- Enzyme activity assay development and functional characterization
Key Technologies
- Chromatography-based protein purification (column and anion-exchange)
- Fluorescent-kinetic collagen degradation activity (CDA) microplate assay
- Protease/peptidase activity assays (Wunsch, FALGPA, FITC-based substrates, BAEE)
- Lyophilization and aseptic fill–finish
News & Updates
VitaCyte will be attending Advanced Therapies USA 2024, focusing on advancing cell and gene therapies.
VitaCyte has rebranded its DE Collagenase to PD Collagenase, reflecting its commitment to providing high-quality, purified enzymes for cell isolation.
Celebrating two decades of innovation and contributions to the field of cell isolation and recovery.
Some products will now be manufactured with plastic flip cap tear-off seal enclosures, making them easier to open in an aseptic environment.
VitaCyte will be attending Advanced Therapies USA 2024, focusing on advancing cell and gene therapies.
VitaCyte has rebranded its DE Collagenase to PD Collagenase, reflecting its commitment to providing high-quality, purified enzymes for cell isolation.
Celebrating two decades of innovation and contributions to the field of cell isolation and recovery.
Some products will now be manufactured with plastic flip cap tear-off seal enclosures, making them easier to open in an aseptic environment.