Scorpius BioManufacturing


Scorpius BioManufacturing is a U.S. biologics CDMO providing cGMP manufacturing, bioanalytical, and process development services for protein modalities. Located in San Antonio, Texas, it specializes in working with emerging biotechs, academic researchers, and U.S. Government institutions. The company emphasizes quality, speed, flexibility, and responsiveness, with capabilities including mammalian and microbial biomanufacturing, analytical services, and a commitment to American-made equipment and consumables. It aims to be a leading CDMO for emerging biotech innovators, supporting the development of safe, high-quality therapies through lifelong partnerships.

Industries

analytics
biotechnology
manufacturing
test-and-measurement

Nr. of Employees

medium (51-250)

Scorpius BioManufacturing

1305 East Houston Street, San Antonio, TX 78205, USA


Products

Biomanufacturing Services

Provides biomanufacturing services from pre-clinical evaluation to commercial manufacturing, integrating analytical methods development, process development, cGMP manufacturing, product characterization, and QC release testing.

Formulation Development

Offers formulation development services for biopharmaceuticals, including therapeutic proteins, enzymes, immunotoxins, monoclonal antibodies, protein-based vaccines, and cell-based therapies.

Analytical Testing

Develops and validates analytical test methods to characterize biologics, including cell therapy products, protein therapeutics, and vaccines, ensuring product quality and consistency.

Clinical-Scale Facility

Operates a clinical-scale biomanufacturing facility with 2,000 sq. ft. of process and analytical development space and 8,600 sq. ft. of cGMP-compliant cleanroom manufacturing space.


Services

End-to-end biologics manufacturing services including upstream, downstream, formulation, and aseptic fill–finish in cGMP cleanrooms for mammalian, microbial, and cell therapy products.

Process development for mammalian and microbial platforms including scale-down modeling, optimization of culture and fermentation conditions, and downstream purification/refolding.

Analytical testing and bioanalysis covering preclinical and clinical phases, GLP-compliant sample analysis, and CMC analytical support for regulatory filings.

Design, optimization, and regulatory-aligned validation of cell-based assays, immunoassays, and molecular assays (qPCR), including multiplexed and automated formats.

Method development, qualification, and validation for CMC and characterization techniques (HPLC, SPR, microscopy) and stability testing programs.

Advisory and hands-on support to execute sponsor-to-manufacturer tech transfers and reduce manufacturing start-up risks.

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Expertise Areas

  • Clinical biomanufacturing
  • Mammalian cell culture and cell therapy manufacturing
  • Microbial fermentation development
  • Upstream and downstream process development
  • Show More (6)

Key Technologies

  • Single-use bioreactors
  • Stainless steel bioreactors
  • Hybrid single-use/stainless production platforms
  • Miniaturized/scale-down bioreactor systems
  • Show More (10)

News & Updates

Scorpius announces the launch of Scorpius Ventures, a new business unit designed to support emerging biotech companies with a flexible American onshoring model.

Scorpius has been selected to join the Medical CBRN Defense Consortium to advance medical countermeasures against chemical, biological, radiological, and nuclear threats.

NightHawk Biosciences announced its name change to Scorpius Holdings, Inc., reflecting its shift into a large molecule biomanufacturing CDMO.

Joe Payne has been promoted to President and COO of Scorpius BioManufacturing.

Capacity, capacity, capacity. This article discusses the need for biologics manufacturing capacity and how Scorpius supports emerging biotechs.

Joe Payne, President & COO of Scorpius, shares insights on creating a culture of quality in biomanufacturing.

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