SynVivo


SynVivo is a pioneering provider of cell-based microfluidic organ-on-chip platforms, delivering biologically realistic microenvironments for real-time study of cellular behavior, drug delivery, and drug discovery. Their proprietary technology bridges microfluidics and bioengineering, enabling advanced research in life sciences, disease modeling, and personalized medicine. SynVivo's chips support microvascular networks that closely mimic in vivo tissue conditions, validated by scientific research to more accurately reflect human biology than conventional culture methods. The platform is especially impactful for personalized cancer therapy, allowing patient-derived cells to be used for drug efficacy testing in a simulated tumor environment. SynVivo also distributes a wide range of high-quality primary cells and cell lines from various species, supporting research in immunology, cardiovascular, and cancer biology.


Patents

Systems and methods for reperfusion injury

2023-10-10 • US-11782051-B2

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Synthetic microfluidic systems for hypoxia

2020-09-15 • US-10775364-B2

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Synthetic microfluidic systems for tumor metastasis

2020-05-05 • US-10641761-B2

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Cell culture device with an array of microfluidic networks

2018-07-03 • US-10012640-B2

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Synthetic microfluidic systems for tumor metastasis

2018-04-03 • US-9933413-B2

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Miniaturized electrothermal flow induced infusion pump

2018-01-30 • US-9878090-B2

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What We Do

A starter kit featuring the SynTumor Cancer-on-a-Chip with microvascular network and 8μm pillar configuration, designed for advanced cancer modeling and research.

A starter kit featuring the SynTumor Cancer-on-a-Chip with microvascular network and 2μm pores, ideal for simulating tumor microenvironments.

A starter kit with SynTumor Cancer-on-a-Chip in an idealized radial 8μm pillar configuration for cancer research applications.

A starter kit with SynTumor Cancer-on-a-Chip in an idealized radial 2μm pore configuration for advanced oncology studies.

A starter kit with SynTumor Cancer-on-a-Chip in a linear 5μm pore configuration, supporting cancer-on-chip research.

A starter kit with SynTumor Cancer-on-a-Chip in a linear 3μm pore configuration for detailed cancer microenvironment modeling.

A comprehensive starter kit for modeling the blood-brain barrier using SynVivo's 3PLEX chip, including chips, pneumatic primer, tubing, slide clamps, needles, syringes, and manifold.

A starter kit for blood-brain barrier modeling using the TEER chip configuration, supporting advanced neuroscience and drug delivery research.

A starter kit for blood-brain barrier modeling using the IMN2 radial chip configuration.

A starter kit for blood-brain barrier modeling using the IMN2 linear chip configuration.

A starter kit for inflammation-on-a-chip studies using the SynRAM microvascular network configuration.

A starter kit for inflammation-on-a-chip studies using the SynRAM radial configuration.

A starter kit for lung-on-a-chip research using the SynALI linear chip configuration.

A starter kit for toxicology-on-a-chip studies using the SynTox radial configuration.

A starter kit for toxicology-on-a-chip studies using the SynTox linear configuration.

Cryopreserved adult human hepatic stellate cells, characterized by Desmin and GFAP, for liver research. Distributed by SynVivo as a distributor of iXCells Biotech.

Cryopreserved human hepatic stellate cells isolated from NASH patient liver tissue, for advanced liver disease research. Distributed by SynVivo as a distributor of iXCells Biotech.

Cryopreserved rat hepatic stellate cells, isolated from young DS rat liver, for liver research. Distributed by SynVivo as a distributor of iXCells Biotech.

High quality cryoplateable primary human hepatocytes, isolated from whole liver of human organ donors, for liver and toxicity research. Distributed by SynVivo as a distributor of iXCells Biotech.

High quality human villous trophoblasts isolated from placental villi and cryopreserved at P1, expressing alpha- and beta-HCG, and negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.

Cryopreserved human villous trophoblasts, isolated from placental villi, for placental and developmental biology research.

Cryopreserved human peripheral blood mononuclear cells (PBMCs) from healthy donors, purified using Ficoll gradient centrifugation. Distributed by SynVivo as a distributor of iXCells Biotech.

Cryopreserved human PBMCs in 15 million cell vials for research use.

Cryopreserved human PBMCs in 25 million cell vials for research use.

Cryopreserved human PBMCs in 50 million cell vials for research use. Purified from peripheral blood using Ficoll gradient centrifugation.

Cryopreserved human PBMCs in 100 million cell vials for research use.

Cryopreserved human PBMCs in 200 million cell vials for research use.

Cryopreserved human PBMCs in 350 million cell vials for research use. Distributed by SynVivo as a distributor of iXCells Biotech.

Cryopreserved human PBMCs in 500 million cell vials for research use.

Cryopreserved pooled human PBMCs from healthy donors, purified using Ficoll gradient centrifugation.

Fresh human PBMCs in 100 million cell vials for research use. Distributed by SynVivo as a distributor of iXCells Biotech.

Fresh human PBMCs in 200 million cell vials for research use.

Fresh human PBMCs in 350 million cell vials for research use. Distributed by SynVivo as a distributor of iXCells Biotech.

Fresh human PBMCs in 500 million cell vials for research use.

Fresh human PBMCs in 700 million cell vials for research use. Distributed by SynVivo as a distributor of iXCells Biotech.

Fresh human PBMCs in 1200 million cell vials for research use.

CD3+ Pan T Cells from human peripheral blood, isolated using negative immunomagnetic selection. Untouched and ready for downstream usage.

CD3+ Pan T Cells from human peripheral blood, available in 40 million cell vials for research use. Isolated using negative immunomagnetic selection and ready for downstream usage.

CD4+ Helper T Cells isolated from human peripheral blood using positive immunomagnetic selection.

Untouched CD4+ Helper T Cells from human peripheral blood, isolated using negative immunomagnetic selection.

CD8+ Cytotoxic T Cells from human peripheral blood, isolated using positive immunomagnetic selection.

CD8+ Cytotoxic T Cells from human peripheral blood, isolated using positive immunomagnetic selection. Passage Number: P0.

Untouched CD8+ Cytotoxic T Cells from human peripheral blood, isolated using negative immunomagnetic selection.

Untouched pan monocytes isolated from human peripheral blood, distributed by SynVivo for research.

Untouched pan monocytes isolated from human peripheral blood, available in 40 million cell vials.

High quality rat PBMCs isolated from Sprague Dawley rat peripheral blood and cryopreserved. Distributed by SynVivo as a distributor of iXCells Biotech.

High quality BAECs isolated from bovine aorta and cryopreserved at P2, negative for mycoplasma, bacteria, yeast, and fungi. Passage Number: P2.

Canine aortic endothelial cells isolated from canine aorta and cryopreserved at P2. Useful for cardiovascular disease research.

Porcine aorta endothelial cells isolated from porcine aorta and cryopreserved at P2, for cardiovascular research.

Rat cardiac fibroblasts isolated and cryopreserved for cardiovascular research.

Mouse cardiac fibroblasts isolated and cryopreserved for cardiovascular research.

Human aortic smooth muscle cells isolated and cryopreserved for vascular research.

Human cardiac microvascular endothelial cells isolated and cryopreserved for cardiovascular research.

A 3D organ-on-chip model for neuroscience research, simulating the blood-brain barrier for drug delivery and disease studies.

A 3D inflammation model for studying leukocyte-endothelium interactions and inflammatory processes.

A 3D cancer model enabling real-time visualization of tumor cluster growth and perfusion for oncology research.

A lung-on-chip model for air-liquid interface studies, including cilia beating and airway research.

A 3D toxicology model for evaluating vascular lumen integrity and toxicological responses under flow conditions.

A range of microfluidic chips including linear channels, bifurcating channels, microvascular networks, and idealized networks for advanced cell culture and tissue modeling.

Supporting instruments such as pneumatic primers, cell impedance analyzers, syringe pumps, and stage top incubators for use with SynVivo chips.

Various accessories to complement SynVivo's organ-on-chip and microfluidic platforms.

Custom screening, assay, and model development services using SynVivo's organ-on-chip platforms for drug discovery and research.

Educational workshops and hands-on training sessions on the use of SynVivo's microfluidic and organ-on-chip technologies.


Digital Health Technologies


News & Updates

A publication highlighting the use of SynVivo's platform to study the effects of the NX210c peptide on blood-brain barrier integrity.

Research article utilizing SynVivo's technology to analyze neutrophil phenotypes in sepsis patients.

Study demonstrating the use of a biomimetic chip for evaluating monoclonal antibody bioavailability, leveraging SynVivo's platform.

SynVivo will participate in the SHOCK 2025 conference in Boston.

SynVivo will attend the BIO International 2025 event in Boston.

SynVivo will be present at the MPS World Summit 2025 in Belgium.

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