Plas-Free Ltd
Plas-Free Ltd is a clinical stage HealthTech company specialized in the development and commercialization of vital fluid absorbent devices for blood purification. Founded in 2017, the company focuses on innovative solutions to improve health outcomes and reduce healthcare costs. Their product pipeline aims to address unmet medical needs, particularly in the treatment of massive bleeding and hyperammonemia. The company has demonstrated significant efficacy in reducing bleeding through its ClearPlasma device, which has shown to decrease blood loss by more than 50% in pre-clinical trials.
Plas-Free Ltd
Wadi El Haj 13, P.O. Box 1252, Nazareth 17111, Israel
What We Do
ClearPlasma is an innovative filtration system that modifies human plasma to improve the treatment of massive bleeding by extracting plasminogen, enhancing coagulation and favoring hemostasis. It is a disposable filter that can be used at the patient's bedside or as part of plasma preparation, ensuring safety and efficacy without altering common clinical practices. Clinical trials have shown that ClearPlasma reduces the amount of bleeding by more than 50% and improves hemodynamic parameters.
The AAPC-300 is a non-pyrogenic, sterile, single-use device designed to remove ammonia from the bloodstream, effectively reducing ammonia levels during hepatic encephalopathy. It can reduce ammonia levels in less than 1.5 hours, preventing significant neurological injury. The device specifically extracts more than 80% of ammonia from plasma fraction, addressing a critical need in acute treatment.
Application Area
Biologics
Key People
CMO and Founder
QA Manager
COO
R&D Manager
News & Updates
Plas-Free has successfully achieved ISO 13485 certification, confirming its management system for medical devices.
PlasFree won first place in the distinguished ENRICH Funding Summit, showcasing its innovative solutions.
EIC Grant
PlasFree won approximately €1.8M grant and an additional €2.1M investment from the EIC for its innovative proposals.
PlasFree finished second in the MedTech Startup Contest, which includes a clinical trial with The Baruch Padeh Medical Center, Poriya.
Clinical Trial Completion
Plas-Free completed the open label phase evaluating ClearPlasma in upper gastrointestinal bleeding, demonstrating safety and initial efficacy.
Plas-Free Ltd has a patent portfolio that includes three pending patents aimed at protecting its innovative technologies in major markets worldwide.