ORF Biologics, Inc.
ORF Biologics, Inc. is a biotechnology company based in Tiffin, Iowa, specializing in the design, development, and manufacturing of advanced biologics for research and therapeutic applications. With over 45 years of industry experience, the company pioneers next-generation biologics, focusing on custom and off-the-shelf solutions for pharmaceutical and biotech companies. ORF Biologics is committed to accelerating scientific discovery through innovative protein engineering, synthetic biology, and rigorous quality control, serving critical fields such as infectious disease, neurodegeneration, regenerative medicine, and biosecurity.
ORF Biologics, Inc.
What We Do
A key member of the TGF-β superfamily, used for stem cell maintenance, differentiation, and various research applications. Available in multiple sizes.
Supports neural development and is used in neuroscience research.
Used in neural development and stem cell research.
Supports stem cell and developmental biology research.
Used in cell culture and regenerative medicine research.
Supports cell proliferation and tissue regeneration studies.
Used in stem cell and iPSC culture, as well as tissue engineering.
Supports angiogenesis and vascular biology research.
Standard cell line for research and production, available with custom-matched growth media.
Widely used cell line for protein expression and research.
Optimized growth medium for CHO-K1 cells.
Optimized growth medium for HEK293 cells.
Development and production of GLP-grade, fully validated custom biologics tailored to specific research or therapeutic needs, including novel therapeutic targets and specialized growth factors. Services include process optimization, modular workflows, and scalable manufacturing for both small and bulk orders.
Provision of ready-to-use, modular, and flexible biologics with consistent performance and rapid availability, supporting research timelines and scalable supply needs.
Specialization in plasmid manufacturing, genetic engineering, and clone optimization for biologic production, ensuring scalable protein expression and high-yield results.
Comprehensive biologics testing, including real-time in-process sampling, final product evaluation, stability testing, and rigorous quality control protocols to ensure protein integrity and functionality.
Development of robust, regulatory-compliant assays and consultancy services for biologics, biosimilars, and novel therapeutics, in partnership with Vipragen Biosciences Pvt. Ltd.
Application Area
Key People
CEO
News & Updates
Announcement of a strategic partnership with Vipragen Biosciences Pvt. Ltd. to accelerate innovation in drug discovery research and assay development, combining expertise in recombinant protein technologies and preclinical research.
Launch of standard CHO-K1 and HEK293 cell lines with custom-matched growth media for research and production environments.
Announcement of innovative approaches to the design and manufacturing of standard and custom biologics, including peptides, proteins, and antibodies.
Open house event on July 18, 2025, offering tours of lab facilities, team meet-and-greet, and insights into the company's mission and work.
Participation in Bio 2025 in Boston from June 16-19, 2025, showcasing advancements in biologics at Exhibitor Booth 1789.