Member

Hyperion Biosystems


Hyperion Biosystems, an MIT spin-out tough tech company, is developing revolutionary diagnostics at the interface of chemistry, biology, and algorithms to address medicine’s most expensive blind spot – sepsis. Our flagship molecular platform (Helios™) is able to simultaneously detect tens to hundreds of target species, direct-from-blood, with excellent sensitivity (single-copy) and specificity (VAFs in excess of 0.0001%). These capabilities are tailer-made for rapid, pre-culture, pathogen identification (ID) and antimicrobial resistance (AMR) marker detection in patients with suspected bloodstream infection (BSI) or sepsis.

Industries

Medical Diagnostics
Sepsis Detection
Antimicrobial Resistance
Infectious Diseases
Biosurveillance
Threat Detection
Bacterial Disease Detection
Fungal Disease Detection
Viral Disease Detection

Nr. of Employees

small (1-50)

Hyperion Biosystems

Hyperion Biosystems is currently seeking investment

Hyperion Biosystems is seeking a series-a investment in the range of 5m-20m

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Products

Low cost, fully connected reader system for rapid diagnostics

A hardware-software integrated reader platform that boosts diagnostic assay sensitivity and specificity, compatible with rapid diagnostic assays.

Helios

Platform molecular technology that leverages a combination of padlock probe chemistry, isothermal amplification, and optical detection to enable pre-culture detection and identification of >95% of sepsis-causing pathogens (bacterial and fungi) at single-copy level with a 3 hour turnaround time.

Authentication and anti-counterfeiting solution for solid oral dosage products

Technology for on-dose authentication to prevent counterfeiting of pharmaceutical and nutraceutical tablets and capsules.

Expertise Areas

  • Diagnostic assay research and development
  • Digital health and connected diagnostics
  • Computer vision in diagnostics
  • Physics-based algorithm design
  • Show More (6)

Key Technologies

  • Computer vision algorithms
  • Physics-based diagnostic algorithms
  • AI-enhanced diagnostic software
  • Isothermal amplification
  • Show More (5)

Key People

Mary Rose Durante

Chief Operations Officer

Robert Deans, Ph.D.

Chief Executive Officer

Joseph Walish, Ph.D.

Chief Technology Officer

Nicole Terry

Engineer

Alex Petty

Scientist

Brian Fratto, Ph.D.

Senior Scientist

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Investors

Series C - Hyperion Biosystems

National Institute of Biomedical Imaging and Bioengineering

Series B - Hyperion Biosystems

Convertible Note - Hyperion Biosystems

Moore Capital, Safar Partners

The Engine

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News & Updates

Algorithms have powered over 10,000 diagnostic assay runs.

Describes the use of smartphone cameras for time-gated luminescence diagnostic measurements.

Entered into a licensing agreement to commercialize a jointly developed anti-counterfeiting technology for pharmaceutical and nutraceutical solid oral dosage products.

Received NIH RADx program award for connected at-home diagnostic reader with multiplex COVID-19/flu A&B rapid test.

Published a study demonstrating time-gated luminescence measurements using smartphone cameras.

Awarded NIH RADx Tech funding to advance a digitally connected at-home reader for improving sensitivity of COVID-19/flu diagnostic tests.

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