Genovac
Genovac is a contract research and manufacturing organization (CRO/CMO) focused on discovery, development, and production of antibodies. The company combines genetic immunization, multiple host species, single B cell screening, hybridoma workflows, and downstream production to generate and characterize antibodies against challenging targets, including multi-pass membrane proteins. Operations include discovery activities in Germany and production and characterization capabilities at a headquarters facility in Fargo, North Dakota.
Industries
Nr. of Employees
medium (51-250)
Products
Catalog antibodies (panel of monoclonal and polyclonal antibodies)
Off-the-shelf panel of characterized antibodies against a range of human and other targets for use in applications such as flow cytometry, ELISA, immunofluorescence, western blot, and immunohistology.
Catalog antibodies (panel of monoclonal and polyclonal antibodies)
Off-the-shelf panel of characterized antibodies against a range of human and other targets for use in applications such as flow cytometry, ELISA, immunofluorescence, western blot, and immunohistology.
Services
Antibody discovery services
Discovery workflows combining genetic immunization, multiple host species options, hybridoma workflows, and single B cell screening to generate antibodies against challenging targets.
Antibody production (HTP, intermediate, scale-up)
Parallel small-scale high-throughput production, intermediate batch production, and scale-up mammalian production with downstream process development support.
Antibody characterization (binding kinetics, epitope binning)
Label-free binding kinetics and epitope binning workflows to support lead selection and epitope mapping using high-throughput SPR and BLI platforms.
Functional assay development and execution
Design and execution of customized functional assays (binding, blocking, neutralization, internalization, cytotoxicity) with multiple detection platforms.
Cell line development
Generation and selection of production cell lines using automated single-cell platforms to support recombinant antibody manufacture.
Cloud-enabled discovery analytics
Integration of cloud-based analytics platforms to accelerate discovery workflows and aid early de-risking of antibody candidates.
Antibody discovery services
Discovery workflows combining genetic immunization, multiple host species options, hybridoma workflows, and single B cell screening to generate antibodies against challenging targets.
Antibody production (HTP, intermediate, scale-up)
Parallel small-scale high-throughput production, intermediate batch production, and scale-up mammalian production with downstream process development support.
Antibody characterization (binding kinetics, epitope binning)
Label-free binding kinetics and epitope binning workflows to support lead selection and epitope mapping using high-throughput SPR and BLI platforms.
Functional assay development and execution
Design and execution of customized functional assays (binding, blocking, neutralization, internalization, cytotoxicity) with multiple detection platforms.
Cell line development
Generation and selection of production cell lines using automated single-cell platforms to support recombinant antibody manufacture.
Cloud-enabled discovery analytics
Integration of cloud-based analytics platforms to accelerate discovery workflows and aid early de-risking of antibody candidates.
Expertise Areas
- Antibody discovery and screening
- Genetic immunization
- Single B cell workflows and single-cell screening
- Hybridoma development
Key Technologies
- Genetic immunization
- Single-cell automated screening platforms
- Hybridoma technology
- Surface plasmon resonance (high-throughput SPR)