Univercells Technologies


Developer of intensified, integrated biomanufacturing platforms and single-use systems for cost‑effective viral vector, vaccine and extracellular vesicle production across R&D to commercial scales. Technologies focus on structured fixed-bed bioreactors, chaining of unit operations, automation and predictive process monitoring to reduce footprint, material use and operational costs. Incorporated in Belgium and now part of Donaldson Life Sciences.

Industries

biotechnology
industrial
manufacturing

Nr. of Employees

medium (51-250)

Univercells Technologies

Chemin de la Vieille Cour 56a and b, 1400 Nivelles, Belgium


Patents

Cell growth matrix

US-12467027-B2

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System and method for the production of biomolecules such as viral vaccines

US-12152231-B2

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System for the production of cells and/or cell products

US-12036549-B2

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Cell growth matrix

US-11827873-B2

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Cell growth matrix

US-10876090-B2

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System, apparatus and method for biomolecules production

US-10494421-B2

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Products

scale‑X hydro system

Small-scale single-use structured fixed-bed bioreactor (≈2.4 m²) for early-stage proof-of-concept and direct process transfer from 2D systems.

scale‑X carbo system

Intermediate-scale, GMP‑compatible single‑use fixed‑bed bioreactor (10–30 m²) with integrated in-line concentration for process development and clinical manufacturing.

scale‑X nexo system

Extra small-scale mini bioreactor (≈0.5 m² surface, ~75 mL volume) for early-stage screening with direct scale-up path to larger fixed-bed systems.

scale‑X nitro controller and large-scale bioreactor

Automation controller designed to operate large-area fixed-bed bioreactors (200 m² and 600 m²) providing a compact, wheeled unit for commercial-scale upstream automation.

cell collect module (seed‑train harvest)

Benchtop cell harvest system for high-yield detachment from fixed-bed substrates to generate inoculum for downstream inoculation with reported high viability and yield.

NevoLine Upstream platform

Compact integrated upstream platform that chains unit operations from inoculation to midstream processing within a small footprint for automated GMP clinical and commercial upstream production.

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Services

Installation, commissioning, process training and maintenance support to enable rapid deployment and reliable operation of biomanufacturing platforms.

Technical support from installation to routine maintenance and process troubleshooting to support development and GMP operations.

Expertise Areas

  • Biomanufacturing platform development
  • Fixed-bed bioreactor engineering
  • Process intensification and integration
  • Automation and centralized process control for upstream manufacturing
  • Show More (8)

Key Technologies

  • Structured fixed-bed bioreactors
  • Single-use, gamma‑irradiated consumables
  • In-line tangential flow filtration (TFF)
  • Automation controllers and centralized control systems
  • Show More (6)

News & Updates

White paper examining how integrated, intensified and automated manufacturing solutions can reduce cost and complexity to improve accessibility of gene therapies.

Technical series covering design principles of structured fixed-bed bioreactors including gas exchange, mixing and scalable process design.

White paper on leveraging small-scale parallel bioreactor systems for reliable and scalable process design and optimization.

Case study describing xeno-free MSC expansion in a fixed-bed bioreactor with rapid attachment, optimized harvesting and predictive bioprocess monitoring.

Webinar and publication presenting approaches for low-footprint, automated extracellular vesicle manufacturing in structured fixed-bed systems.

Guidance on harvest optimization to improve recovery, reduce volumes and manage impurity profiles for AAV manufacturing in fixed-bed systems.

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