Synta Pharmaceuticals Corp.
Madrigal Pharmaceuticals is a biopharmaceutical company dedicated to delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease. The company aims to halt or reverse liver scarring and has developed the first FDA-approved treatment for MASH. With a focus on innovation, collaboration, and patient-centered care, Madrigal is leading the fight against MASH through extensive research, clinical trials, and community engagement.
Industries
Nr. of Employees
large (251-1000)
Synta Pharmaceuticals Corp.
200 Barr Harbor Drive, Suite 200, West Conshohocken, PA 19428
Patents
Methods of treating liver disorders or lipid disorders with a THR-beta agonist
US-11806353-B2
View DetailsMethods of treating liver disorders or lipid disorders with a THR-beta agonist
US-11090308-B2
View Details
Methods of treating liver disorders or lipid disorders with a THR-beta agonist
US-11806353-B2
View DetailsMethods of treating liver disorders or lipid disorders with a THR-beta agonist
US-11090308-B2
View DetailsProducts
FDA‑approved oral liver‑directed therapy for adults with MASH
An orally administered, liver‑directed small‑molecule THR‑β agonist therapy approved by the U.S. Food and Drug Administration for treatment of adults with metabolic dysfunction‑associated steatohepatitis (MASH).
FDA‑approved oral liver‑directed therapy for adults with MASH
An orally administered, liver‑directed small‑molecule THR‑β agonist therapy approved by the U.S. Food and Drug Administration for treatment of adults with metabolic dysfunction‑associated steatohepatitis (MASH).
Services
Support services for patients including diagnosis assistance, affordability and copay support, educational resources and a dedicated patient support website.
Provision of prescribing information and a channel for medical information requests for healthcare professionals.
Dedicated phone line and processes for reporting adverse events, product quality issues and other safety-related information.
Online application process for sponsorships, patient advocacy grants, R&D grants, medical education grants and investigator‑initiated study funding.
Support services for patients including diagnosis assistance, affordability and copay support, educational resources and a dedicated patient support website.
Provision of prescribing information and a channel for medical information requests for healthcare professionals.
Dedicated phone line and processes for reporting adverse events, product quality issues and other safety-related information.
Online application process for sponsorships, patient advocacy grants, R&D grants, medical education grants and investigator‑initiated study funding.
Expertise Areas
- Clinical trial management for liver disease
- Small‑molecule drug discovery and liver‑directed pharmacology
- Regulatory affairs and FDA approval strategy
- Medical affairs and pharmacovigilance
Key Technologies
- Small‑molecule THR‑β (thyroid hormone receptor‑β) agonists
- Liver‑directed pharmacology
- Oral small‑molecule therapeutics
- Phase 3 clinical development platforms