SpectraGenetics, Inc.
SpectraGenetics is dedicated to providing innovative tools for drug discovery and development. Their proprietary platforms enable high-throughput, multiplexed analysis of receptor internalization kinetics in living cells, facilitating target identification, lead discovery, and selectivity determination. They have developed a comprehensive catalog of FAP-tagged human GPCRs, including over 350 plasmids and 100 validated human cell lines, to accelerate research in both academic and industrial settings. The company actively collaborates with academic institutions like Carnegie Mellon University and supports open scientific projects, emphasizing innovation and scientific progress.
Industries
Nr. of Employees
small (1-50)
SpectraGenetics, Inc.
Products
Plasmid and vector construct catalog
Commercial catalog of plasmid vectors engineered to express human receptors with tags compatible with fluorescent labeling for use in cellular pharmacology and imaging assays.
Validated mammalian cell line catalog
Catalog of validated human and mammalian cell lines engineered to express tagged receptors for functional and internalization assays, offered as ready-to-use models.
Fluorogen reagent catalog
Commercial supply of fluorogenic reagents designed for use with tag-based labeling approaches to label and detect tagged proteins in live-cell assays.
Plasmid and vector construct catalog
Commercial catalog of plasmid vectors engineered to express human receptors with tags compatible with fluorescent labeling for use in cellular pharmacology and imaging assays.
Validated mammalian cell line catalog
Catalog of validated human and mammalian cell lines engineered to express tagged receptors for functional and internalization assays, offered as ready-to-use models.
Fluorogen reagent catalog
Commercial supply of fluorogenic reagents designed for use with tag-based labeling approaches to label and detect tagged proteins in live-cell assays.
Services
Cloning and cell line construction services
Contract services for design/cloning of constructs and custom mammalian cell-line construction to express tagged receptors for research assays, including validation for assay use.
Cloning and cell line construction services
Contract services for design/cloning of constructs and custom mammalian cell-line construction to express tagged receptors for research assays, including validation for assay use.
Expertise Areas
- GPCR pharmacology
- High-throughput live-cell assay development
- Plasmid and construct library generation
- Mammalian cell model engineering and validation
Key Technologies
- Live-cell receptor internalization assays
- Multiplexed high-throughput screening
- Fluorogen-activating tag-based fluorescence labeling
- Plasmid and vector cloning