Shimojani


Shimojani LLC is a biotech company focused on developing therapies to reduce hemorrhage risk in acute ischemic stroke patients. They have licensed a novel invention from Niigata University that targets a key pathway involved in stroke severity, aiming to advance this work into clinical trials to improve survival and quality of life for stroke victims.

Industries

biotechnology

Shimojani

San Francisco, California, United States, North America


Products

Licensed therapeutic program to reduce hemorrhagic conversion in acute ischemic stroke

An academic-origin therapeutic program licensed for development and commercialization aimed at reducing hemorrhagic conversion in acute ischemic stroke patients, including those treated with thrombolytic agents; program is in preclinical and IND-enabling development.


Services

Preclinical development and translational research for stroke therapeutics

Validation and advancement of therapeutic candidates from animal models toward IND-enabling studies, including biomarker analysis and coordination with clinical experts.

Expertise Areas

  • Acute ischemic stroke therapeutics
  • Preclinical model development and validation
  • IND-enabling development and regulatory strategy
  • Biomarker-driven translational validation
  • Show More (2)

Key Technologies

  • Rodent ischemic stroke models
  • Signal transduction pathway analysis
  • Biomarker assays for pathway activation
  • Small-molecule drug evaluation
  • Show More (2)

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