Saretius
Saretius is a UK-based company established in 2008, specializing in preclinical experimental services for drug discovery. With a team of experienced scientists and a track record of working with over 80 clients across biotech, pharma, academia, and CRO organizations, Saretius offers integrated services from target validation to clinical development. The company emphasizes biomarker, pharmacokinetic, and pharmacodynamic studies, and operates state-of-the-art facilities at the University of Reading. Their mission is to provide bespoke, high-quality drug discovery solutions across a wide range of therapeutic areas, including metabolism, immunology, neurology, psychiatry, pain, and dermatology.
Industries
Nr. of Employees
small (1-50)
Saretius
Services
Design and conduct of rat and mouse PK/ADME studies with multiple administration routes, serial and terminal sampling, metabolism/excretion endpoints and flexible bioanalytical arrangements.
Bespoke biomarker and pharmacodynamic assay development and deployment for in vitro, ex vivo and in vivo studies, including measurement of cytokines, behavior, biochemical markers, immune cell responses and mRNA expression.
Provision of rodent disease models across therapeutic areas and side-effect profiling services to support efficacy and safety assessment and therapeutic index determination.
Specialist in vivo and ex vivo services tailored to specific therapeutic areas including immunology and inflammation, dermatology, neurology, psychiatry, pain, and metabolism/endocrinology.
Scientific and strategic consulting services including review of discovery and development portfolios and study design advice for preclinical progression.
Design and conduct of rat and mouse PK/ADME studies with multiple administration routes, serial and terminal sampling, metabolism/excretion endpoints and flexible bioanalytical arrangements.
Bespoke biomarker and pharmacodynamic assay development and deployment for in vitro, ex vivo and in vivo studies, including measurement of cytokines, behavior, biochemical markers, immune cell responses and mRNA expression.
Provision of rodent disease models across therapeutic areas and side-effect profiling services to support efficacy and safety assessment and therapeutic index determination.
Specialist in vivo and ex vivo services tailored to specific therapeutic areas including immunology and inflammation, dermatology, neurology, psychiatry, pain, and metabolism/endocrinology.
Scientific and strategic consulting services including review of discovery and development portfolios and study design advice for preclinical progression.
Expertise Areas
- Preclinical pharmacokinetics (rodent PK studies)
- Biomarker and pharmacodynamic assay development
- Preclinical disease modeling and translational efficacy testing
- Side-effect profiling and therapeutic index determination
Key Technologies
- Serial blood and tissue sampling
- Vascular cannulation techniques (jugular, femoral, hepatic portal)
- Bile and metabolic cage sampling for excretion studies
- Bioanalytical assays for metabolite identification
News & Updates
The latest update on Saretius' advanced laboratory facilities at the University of Reading.
The latest update on Saretius' advanced laboratory facilities at the University of Reading.