Santa Cruz Biotechnology (SCBT)
Santa Cruz Biotechnology Inc. is a leading provider of research reagents, including antibodies, proteins, gene editing products, and chemical compounds, supporting scientific research across various disciplines. The company offers a broad range of products such as CRISPR plasmids, inhibitors, substrates, antibodies, probes, and specialized tools for stem cell and gene silencing research. With a commitment to quality and innovation, Santa Cruz Biotechnology aims to provide researchers with the tools necessary to explore cellular mechanisms, enzyme functions, signaling pathways, and disease processes, advancing scientific understanding in molecular biology, biochemistry, neuroscience, cell biology, and biomedical research.
Industries
Nr. of Employees
large (251-1000)
Santa Cruz Biotechnology (SCBT)
Products
CRISPR reagent kits (plasmids and viral particles)
Plasmids for knockout, activation, HDR and double‑nickase workflows and corresponding lentiviral activation/knockout particles for delivery in cultured cells and model organisms.
RNAi reagents and shRNA lentiviral particles
Chemically synthesized siRNAs, shRNA expression plasmids and lentiviral shRNA particles with selectable markers for transient or stable gene knockdown across species.
Antibodies validated for WB/IP/IF/IHC/FCM/ELISA
Primary and secondary monoclonal and polyclonal antibodies with application and species validation information for use as detection reagents in immunoassays.
Recombinant proteins and transfected lysates
Purified recombinant protein fragments and transfected cell lysates supplied as assay controls or standards for biochemical and immunological assays.
Gel-shift oligonucleotides and binding sequence reagents
Consensus and mutant oligonucleotides for electrophoretic mobility shift assays (EMSA) and DNA‑binding studies.
Small molecules, assay substrates and labeled compounds
Research‑grade small‑molecule inhibitors, chromogenic/fluorogenic substrates and isotopically labeled compounds for biochemical assays, imaging and mass spectrometry.
CRISPR reagent kits (plasmids and viral particles)
Plasmids for knockout, activation, HDR and double‑nickase workflows and corresponding lentiviral activation/knockout particles for delivery in cultured cells and model organisms.
RNAi reagents and shRNA lentiviral particles
Chemically synthesized siRNAs, shRNA expression plasmids and lentiviral shRNA particles with selectable markers for transient or stable gene knockdown across species.
Antibodies validated for WB/IP/IF/IHC/FCM/ELISA
Primary and secondary monoclonal and polyclonal antibodies with application and species validation information for use as detection reagents in immunoassays.
Recombinant proteins and transfected lysates
Purified recombinant protein fragments and transfected cell lysates supplied as assay controls or standards for biochemical and immunological assays.
Gel-shift oligonucleotides and binding sequence reagents
Consensus and mutant oligonucleotides for electrophoretic mobility shift assays (EMSA) and DNA‑binding studies.
Small molecules, assay substrates and labeled compounds
Research‑grade small‑molecule inhibitors, chromogenic/fluorogenic substrates and isotopically labeled compounds for biochemical assays, imaging and mass spectrometry.
Services
Technical support and protocols
Online experimental protocols, technical help resources and webinar materials to support reagent selection and experimental workflows.
Datasheet, SDS and product citation search
Online access to product datasheets, safety data sheets and searchable literature citations referencing specific reagents.
Customer care and ordering support
Phone and online customer service for account management, ordering, returns and shipping support.
Webinars and educational resources
Recorded and live webinar content focused on reagent applications and assay workflows.
Technical support and protocols
Online experimental protocols, technical help resources and webinar materials to support reagent selection and experimental workflows.
Datasheet, SDS and product citation search
Online access to product datasheets, safety data sheets and searchable literature citations referencing specific reagents.
Customer care and ordering support
Phone and online customer service for account management, ordering, returns and shipping support.
Webinars and educational resources
Recorded and live webinar content focused on reagent applications and assay workflows.
Expertise Areas
- CRISPR-based genome editing and activation (knockout, activation, HDR, double‑nickase)
- RNA interference and lentiviral-mediated gene silencing
- Antibody reagents and validation for WB/IP/IF/IHC/FCM/ELISA
- Recombinant protein controls and transfected lysates for assays
Key Technologies
- CRISPR/Cas9 genome editing
- CRISPR activation (CRISPRa/dCas9 activators)
- Homology-directed repair (HDR) plasmid templates
- Double-nickase CRISPR design