React4life
React4life is an innovative Italian biotech company founded in 2016, specializing in the development of advanced organ-on-chip technology called MIVO®. The company's mission is to create reliable, predictive in vitro models of human biology to support biomedical research, drug development, personalized medicine, and cosmetic testing, ultimately reducing the reliance on animal testing and improving the accuracy of preclinical studies.
Industries
Nr. of Employees
small (1-50)
Products
Multi-chamber fluidic organ-on-chip platform
A patented millifluidic multi-chamber device engineered to host 3D tissue constructs and enable independent fluid control, donor/receiver compartment assays, multi-device interconnection and simulation of systemic circulation for in vitro studies.
MIVO
MIVO millifluidic technology provides more predictive results with high accuracy and reliability for dynamic in vitro cell culture and assays.
MIVO Single-Organ Platform
Single-organ model allowing controlled culture of cells and tissues under physiological conditions with separate apical and basal chambers.
MIVO IMMUNO-OOC
A multi-organ-on-chip platform designed to test immunotherapies and recapitulate the immune cells infiltration and activation against tumour cells in a 3D, fully humanized, and fluid-dynamic environment.
Gut On Chip
An in vitro millifluidic cell culture solution to study the physiological and pathological environment of the gut, intestinal permeability, gut barrier function, and molecular transport under dynamic conditions.
Gut Anti-inflammatory Assay
A dynamic multicellular intestinal 3D model utilizing the MIVO platform to evaluate the impact of treatments on intestinal tissue functionality, healthy state, and inflammation recovery.
Multi-chamber fluidic organ-on-chip platform
A patented millifluidic multi-chamber device engineered to host 3D tissue constructs and enable independent fluid control, donor/receiver compartment assays, multi-device interconnection and simulation of systemic circulation for in vitro studies.
MIVO
MIVO millifluidic technology provides more predictive results with high accuracy and reliability for dynamic in vitro cell culture and assays.
MIVO Single-Organ Platform
Single-organ model allowing controlled culture of cells and tissues under physiological conditions with separate apical and basal chambers.
MIVO IMMUNO-OOC
A multi-organ-on-chip platform designed to test immunotherapies and recapitulate the immune cells infiltration and activation against tumour cells in a 3D, fully humanized, and fluid-dynamic environment.
Gut On Chip
An in vitro millifluidic cell culture solution to study the physiological and pathological environment of the gut, intestinal permeability, gut barrier function, and molecular transport under dynamic conditions.
Gut Anti-inflammatory Assay
A dynamic multicellular intestinal 3D model utilizing the MIVO platform to evaluate the impact of treatments on intestinal tissue functionality, healthy state, and inflammation recovery.
Services
Design and execution of customized in vitro assays using perfused 3D tissue models to evaluate absorption, toxicity, drug efficacy and cosmetic protection.
Hands-on workshops teaching device operation, 3D culture techniques, microfluidic setups and experimental planning for researchers adopting perfused in vitro systems.
Commercial distribution through partnerships to make perfused organ-on-chip platforms accessible to universities, CROs and companies.
Design and execution of customized in vitro assays using perfused 3D tissue models to evaluate absorption, toxicity, drug efficacy and cosmetic protection.
Hands-on workshops teaching device operation, 3D culture techniques, microfluidic setups and experimental planning for researchers adopting perfused in vitro systems.
Commercial distribution through partnerships to make perfused organ-on-chip platforms accessible to universities, CROs and companies.
Expertise Areas
- Organ-on-chip and microphysiological systems
- 3D cell culture and organoids
- In vitro ADME and permeability testing
- Oncology models and immuno-oncology assays
Key Technologies
- Millifluidic multi-chamber organ-on-chip platforms
- Perfusion bioreactors (peristaltic/syringe pump integration)
- 3D cell culture and patient-derived organoids
- Co-culture systems (tumor–immune interactions)