Pro Test Diagnostics AB
Umeå-based diagnostics company developing a laboratory test kit to detect autologous blood transfusion (autologous blood doping). The approach is based on proteomics profiling of red blood cells using liquid chromatography–mass spectrometry, curated sample-preparation workflows, statistical multivariate models and ongoing work to incorporate machine learning for pre-sorting of blood-cell features. The company is in validation and pilot-production activities and collaborates with accredited anti-doping laboratories and funding bodies.
Industries
Nr. of Employees
small (1-50)
Pro Test Diagnostics AB
Products
Diagnostic test kit for detection of autologous blood transfusion
Laboratory test kit that analyzes molecular fingerprints in blood to detect changes associated with frozen storage and retransfusion of an individual's own blood.
Pro Test Diagnostics blood doping test kit
A diagnostic test kit developed to detect autologous blood doping by measuring unique biomarkers for long-term freeze storage of red blood cells.
nano-ACQUITY Ultra Performance UPLC
An ultra performance liquid chromatography system used for the physical separation of peptides on a reverse phase column.
nano-UPLC Synapt G2
A mass spectrometry system utilizing ESI-Qtof mass spectrometry and MSE for increased detection performance of low abundance proteins and peptides, as well as simultaneous identification and sequencing.
Diagnostic test kit for detection of autologous blood transfusion
Laboratory test kit that analyzes molecular fingerprints in blood to detect changes associated with frozen storage and retransfusion of an individual's own blood.
Pro Test Diagnostics blood doping test kit
A diagnostic test kit developed to detect autologous blood doping by measuring unique biomarkers for long-term freeze storage of red blood cells.
nano-ACQUITY Ultra Performance UPLC
An ultra performance liquid chromatography system used for the physical separation of peptides on a reverse phase column.
nano-UPLC Synapt G2
A mass spectrometry system utilizing ESI-Qtof mass spectrometry and MSE for increased detection performance of low abundance proteins and peptides, as well as simultaneous identification and sequencing.
Services
Joint validation projects and method evaluations with WADA-accredited and hospital-affiliated doping laboratories to verify test performance.
Joint validation projects and method evaluations with WADA-accredited and hospital-affiliated doping laboratories to verify test performance.
Expertise Areas
- Anti-doping diagnostics for autologous blood transfusion
- Mass spectrometry–based proteomics
- Biomarker discovery for sample storage effects
- Proteomics sample preparation
Key Technologies
- Liquid chromatography–mass spectrometry (LC-MS/MS)
- Nano-UPLC
- ESI-QTOF mass spectrometry
- Label-free proteomics
News & Updates
Awarded SEK 1.2 million from WADA to develop a test using AI to pre-sort blood cells and detect changes from frozen storage.
Completed a pilot production run of diagnostic kits with an ISO-certified manufacturing partner to prepare for serial production and laboratory testing.
Entered supply agreement to incorporate hemoglobin-depletion sample-preparation consumables into the testing workflow.
Preprint and submitted manuscript describing a nano-UPLC-MS/MS method separating doped from non-doped samples and demonstrating classification performance.
Raised capital (SEK 17 million) to support development and market preparation of the diagnostic kit.
Received funding from the World Anti-Doping Agency to develop AI-based pre-sorting of blood cells for detection of cryopreserved blood.
Awarded SEK 1.2 million from WADA to develop a test using AI to pre-sort blood cells and detect changes from frozen storage.
Completed a pilot production run of diagnostic kits with an ISO-certified manufacturing partner to prepare for serial production and laboratory testing.
Entered supply agreement to incorporate hemoglobin-depletion sample-preparation consumables into the testing workflow.
Preprint and submitted manuscript describing a nano-UPLC-MS/MS method separating doped from non-doped samples and demonstrating classification performance.
Raised capital (SEK 17 million) to support development and market preparation of the diagnostic kit.
Received funding from the World Anti-Doping Agency to develop AI-based pre-sorting of blood cells for detection of cryopreserved blood.