Kbiobox


KBioBox is a bioinformatics technology company specializing in fast, accurate genomic search and analysis solutions. Their proprietary BioEngine software enables real-time, high-speed genome analysis, off-target effects prediction, gene design, and pathogen identification, supporting research, biotech, and pharmaceutical applications. The company's mission is to eliminate research bottlenecks and empower results through innovative technology licensing and solutions.

Industries

analytics
biopharma
biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

Kbiobox

Worcester, Massachusetts, United States, North America


Patents

Method and system for rapid searching of genomic data and uses thereof

US-10453559-B2

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Method and system for rapid searching of genomic data and uses thereof

US-9529891-B2

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Products

Proprietary bioinformatics engine (search platform)

A platform-level genomic search engine providing high-speed, high-accuracy sequence search and matching capabilities for integration into downstream tools and pipelines.

Off-target analysis tool

A software tool that identifies and reports potential off-target editing sites for proposed guides, including annotation and optional primer calculations.

Guide design tool

Automated calculation of prioritized guide/target candidates based on off-target potential and other selection criteria, returning a ranked list of top candidates.

Extended GUIDE-seq analysis tool

A post-edit analytics tool that processes GUIDE-seq or similar datasets to report cleavage site locations, frequencies, repair characterization, and translocation events.


Services

Design of candidate gene-editing guides prioritized for minimal off-target potential; each design accompanied by off-target analysis to support downstream validation.

Rapid computational screening of proposed targets across one or more genomes to identify potential off-target loci, returning annotated reports and optional primer information.

Analysis of GUIDE-seq or similar experimental outputs to extract cleavage sites, cleavage frequency, repair outcomes, and translocation information.

Development and deployment of custom bioinformatics applications or connectors that embed high-performance search capabilities into existing workflows and products.

Expertise Areas

  • Bioinformatics for genomic search and matching
  • Gene-editing guide design and off-target analysis
  • NGS data analysis and interpretation
  • De novo genome assembly
  • Show More (6)

Key Technologies

  • Proprietary genomic search algorithms
  • Real-time genome-scale sequence search
  • Off-target prediction algorithms
  • Guide/target design algorithms
  • Show More (7)

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