Institut du Cerveau


Research and medical center focused on basic, translational and clinical neuroscience. Activities include laboratory research, clinical cohorts and trials, specialized technological platforms (genomics, imaging, biobank), clinical diagnostics and multidisciplinary care, and programs to accelerate translation from research to development.

Industries

biotechnology
medical
neuroscience-e37a
non-profit

Nr. of Employees

large (251-1000)

Institut du Cerveau


Patents

Orthobunyavirus in human encephalitis and its diagnostic and therapeutic applications

US-12529114-B2

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Diet controlled expression of a nucleic acid encoding a pro-apoptotic protein

US-12419971-B2

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Method for identification of pathological brain activity from scalp electroencephalogram

US-11684303-B2

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System and method for calculation of an index of brain activity

US-11642073-B2

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Method and device for enhancing memory consolidation

US-11612743-B2

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System and methods for consciousness evaluation in non-communicating subjects

US-11559244-B2

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Products

Diagnostic sequencing panel (multi-gene kit)

A diagnostic sequencing panel capable of sequencing known disease-associated genes for molecular diagnosis of hereditary neurological disorders.


Services

Clinical trial design and execution support for early-phase studies, medical writing and coordination of multidisciplinary clinical assessments.

Multimodal diagnostic evaluations combining neuropsychological testing, neuroimaging, oculomotor recording and neurophysiology to support differential diagnosis and patient stratification.

Design and conduct of neuromodulation studies and iterative stimulation protocols to evaluate therapeutic effects on cognition and motor symptoms.

High-throughput genotyping and sequencing services including multi-gene diagnostic panels and rapid sequencing workflows used for molecular diagnosis and research.

Storage, annotation and provision of DNA and cellular samples for research and clinical projects with certified procedures.

Research and development support for blood-based prion detection assays and downstream validation pathways.

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Expertise Areas

  • Clinical trial management in neuroscience
  • Longitudinal cohort design and cohort management
  • Neuroimaging and quantitative image analysis
  • Clinical neurophysiology and oculomotor assessment
  • Show More (8)

Key Technologies

  • Magnetic resonance imaging (MRI)
  • Positron emission tomography (PET)
  • Functional brain imaging (fMRI, functional PET)
  • Electroencephalography (EEG) and intracerebral recordings
  • Show More (8)

News & Updates

Hosted the fifth edition of a charity speedrun marathon to raise funds for neuroscience research.

Announcement that internal platforms received ISO 9001 certification for a quantitative analysis platform and ISO 20387 for the DNA & cells biobank.

Selection of a translational project targeting remyelinating treatment in multiple sclerosis to receive support from the institute's startup studio.

Regulatory authorization was obtained to initiate a phase 2a clinical study of a small-molecule candidate targeting tau phosphorylation in progressive supranuclear palsy; the study includes tolerability, pharmacokinetics and biomarker assessments.

Research teams contributed to development of a biological test able to detect variant prions in blood for diagnosis of prion disease.

Research teams identified new genes implicated in frontotemporal degeneration and other neurogenetic disorders, advancing diagnostic capabilities.

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