Immudex


Immudex specializes in high-quality tools and technologies for immune monitoring, focusing on antigen-specific T and B cells, TCR and antibody discovery, and immune response analysis. Their products, such as Dextramer® reagents, enable detailed characterization of immune responses in various disease areas including cancer, infectious diseases, and autoimmunity. They support research, clinical diagnostics, and therapeutic development with a broad portfolio of reagents, services, and educational resources. The company is committed to empowering researchers and clinicians worldwide to push the boundaries of medicine through advanced immune-based tools, fostering innovation, impact, and community collaboration.

Industries

Biotechnology
Health Diagnostics
Therapeutics
Biotechnology Research

Nr. of Employees

small (1-50)

Immudex

Copenhagen, Capital Region of Denmark, Denmark


Patents

Panel comprising Borrelia MHC multimers

US-12258373-B2

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General detection and isolation of specific cells by binding of labeled molecules

US-11668705-B2

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General detection and isolation of specific cells by binding of labeled molecules

US-11585806-B2

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General detection and isolation of specific cells by binding of labeled molecules

US-11402373-B2

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Combinatorial analysis and repair

US-10722562-B2

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Products

MHC class I multimer reagents for flow cytometry

Pre-assembled multimer reagents presenting MHC class I–peptide complexes for detection and isolation of CD8+ antigen-specific T cells by flow cytometry.

MHC class II multimer reagents for flow cytometry

Multimer reagents presenting MHC class II–peptide complexes for detection of CD4+ antigen-specific T cells.

Loadable peptide–MHC monomers and peptide-loading reagents

Peptide-receptive MHC monomers and loading reagents that allow users to assemble custom multimer libraries with chosen peptides.

DNA-barcoded multimer reagents for NGS and single-cell multi-omics

Multiplexed, DNA-barcoded multimer reagents compatible with sequencing readouts and single-cell multi-omics workflows to map antigen–receptor interactions at scale.

Multimer backbone reagents with antigen-loading acceptor sites

Backbone reagents with multiple acceptor sites for loading biotinylated antigens to detect and isolate antigen-specific B cells and other cell types by flow cytometry or sequencing-based readouts.

GMP-grade multimer reagents and clinical kits

Clinical-grade reagents and kits manufactured under GMP for clinical testing and lot-release support.

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Services

Design and manufacture of allele-specific multimer reagents to support antigen-specific detection and research assays.

Production of reagents derived from customer-provided TCR sequences for detection and monitoring of receptor-specific interactions.

Contracted screening assays to evaluate peptide–MHC binding and prioritize candidate epitopes for downstream validation.

Custom reagent design and manufacture for detection of engineered receptors (e.g., CARs) and other engineered cell-surface targets.

Inter-laboratory proficiency testing and panel distribution for multimer assays and ELISpot to support assay benchmarking and QA.

Consulting and custom library construction to integrate antigen-specific staining with single-cell gene expression and V(D)J sequencing workflows.

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Expertise Areas

  • Precision cellular immune monitoring
  • TCR and BCR discovery and repertoire sequencing
  • Epitope discovery and pMHC binding validation
  • Single-cell multi-omics integration linking specificity to phenotype
  • Show More (6)

Key Technologies

  • Flow cytometry and FACS sorting
  • DNA barcoding for multiplexed reagent libraries
  • Next-generation sequencing (NGS) readout
  • Single-cell RNA-seq and multi-omics integration
  • Show More (6)

News & Updates

High Impact Publications in Nature and Science

Over 20% of papers studying antigen-specific T cells using MHC Dextramer® are published in high impact journals like Nature and Science.

Customer Satisfaction and Reliability

Customer testimonials highlight the quality of products and support, emphasizing reliability in research and clinical applications.

Partnership with Immatics

Immatics uses Dextramer® reagents for lot-release testing of TCR-based cell therapy product candidates, indicating high-quality standards.


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