i2o Therapeutics


i2o Therapeutics, Inc. is focused on developing GLP-1 combinations for obesity and cardio-renal-metabolic diseases. They have a pipeline that includes long-acting GLP-1 receptor agonists, long-acting amylin DACRAs, long-acting PYY receptor agonists, and long-acting glucagon receptor agonists. The company is working on innovative therapies in the metabolic disease space, with new website and corporate news coming soon.

Industries

biotechnology
health-care
therapeutics

Nr. of Employees

small (1-50)

i2o Therapeutics

Allston, Massachusetts, United States, North America


Products

Long-acting GLP-1 receptor agonists (2 assets)

Two long-acting peptide assets designed to activate the GLP-1 receptor with extended duration of action for metabolic disease indications.

Long-acting amylin DACRAs (2 assets)

Two long-acting amylin dual-agonist (DACRA) peptide assets intended for modulation of amylin receptor pathways in metabolic disease.

Long-acting PYY receptor agonist (1 asset)

A long-acting peptide asset targeting peptide YY (PYY) receptor pathways for potential use in metabolic disease treatment.

Long-acting glucagon receptor agonist (1 asset)

A long-acting peptide asset designed to activate the glucagon receptor with extended duration, intended for cardio-renal-metabolic disease applications.

Expertise Areas

  • Peptide therapeutic development
  • Metabolic and obesity therapeutics
  • Combination therapy design
  • Early-stage asset and portfolio management

Key Technologies

  • Peptide therapeutics
  • Extended half-life / long-acting modalities
  • Receptor agonist modalities (GLP-1, amylin, PYY, glucagon)
  • Combination therapeutic platforms

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