GeneOne Life Science
GeneOne Life Science is a global leader in the research, development, and manufacturing of nucleic-acid based vaccines, therapeutics, and novel small molecule drugs. The company focuses on next-generation biopharmaceuticals, including DNA and RNA vaccines for emerging infectious diseases, and nucleic acid therapeutics such as monoclonal antibodies and recombinant proteins. With a strong emphasis on innovation, quality, and integrity, GeneOne aims to improve human health worldwide and establish itself as a leading biotech company.
Industries
Nr. of Employees
small (1-50)
Products
Nucleic-acid vaccine pipeline for multiple viral diseases
Pipeline of DNA- and RNA-based vaccine candidates targeting a range of viral diseases (including coronaviruses, flaviviruses and tick-borne viruses) at preclinical and early clinical stages.
Plasmid-encoded therapeutics and recombinant protein programs
R&D programs delivering recombinant proteins and monoclonal antibodies via plasmid vectors for oncology, hemophilia, hepatitis and autoimmune indications; programs in discovery and early development.
Small-molecule immunomodulators and nasal spray programs
Small-molecule candidates for inflammatory and infectious respiratory/renal conditions and nasal spray formulations that stimulate epithelial innate immunity for prophylaxis and treatment.
Plasmid DNA cGMP manufacturing
Plasmid DNA cGMP production utilizing AirMix technology and production optimization for gene and cell therapy raw materials.
AirMix Plasmid DNA cGMP Production
cGMP production of plasmid DNA utilizing proprietary AirMix technology to meet the rapidly growing demand for gene and mRNA therapies.
mRNA cGMP Production
mRNA cGMP manufacturing services utilizing plasmid DNA as a template for IVT (in vitro transcription) processes.
Nucleic-acid vaccine pipeline for multiple viral diseases
Pipeline of DNA- and RNA-based vaccine candidates targeting a range of viral diseases (including coronaviruses, flaviviruses and tick-borne viruses) at preclinical and early clinical stages.
Plasmid-encoded therapeutics and recombinant protein programs
R&D programs delivering recombinant proteins and monoclonal antibodies via plasmid vectors for oncology, hemophilia, hepatitis and autoimmune indications; programs in discovery and early development.
Small-molecule immunomodulators and nasal spray programs
Small-molecule candidates for inflammatory and infectious respiratory/renal conditions and nasal spray formulations that stimulate epithelial innate immunity for prophylaxis and treatment.
Plasmid DNA cGMP manufacturing
Plasmid DNA cGMP production utilizing AirMix technology and production optimization for gene and cell therapy raw materials.
AirMix Plasmid DNA cGMP Production
cGMP production of plasmid DNA utilizing proprietary AirMix technology to meet the rapidly growing demand for gene and mRNA therapies.
mRNA cGMP Production
mRNA cGMP manufacturing services utilizing plasmid DNA as a template for IVT (in vitro transcription) processes.
Services
Commercial and clinical-grade production of high-purity plasmid DNA and support for mRNA manufacturing including IVT template supply, scale-up, and cGMP quality systems.
Support for preclinical immunogenicity and challenge studies, translation to Phase I/IIa trials, clinical trial conduct and generation of peer-reviewed clinical data.
Discovery, formulation and clinical development support for small-molecule anti-inflammatory candidates and topical nasal sprays targeting innate immune pathways.
Commercial and clinical-grade production of high-purity plasmid DNA and support for mRNA manufacturing including IVT template supply, scale-up, and cGMP quality systems.
Support for preclinical immunogenicity and challenge studies, translation to Phase I/IIa trials, clinical trial conduct and generation of peer-reviewed clinical data.
Discovery, formulation and clinical development support for small-molecule anti-inflammatory candidates and topical nasal sprays targeting innate immune pathways.
Expertise Areas
- Nucleic-acid vaccine development
- Plasmid-based therapeutics and DNA-encoded antibodies
- cGMP plasmid and mRNA manufacturing and CDMO services
- Preclinical immunology and animal challenge models (rodent and ferret)
Key Technologies
- Plasmid vector design and optimization
- In vitro transcription (IVT) workflows for mRNA production
- High-purity plasmid DNA cGMP production
- Automated mixing-based bioprocess for plasmid manufacture