Gene Weaver


Developer of a naturally derived, programmable enzymatic platform for controlled cutting and precision insertion of large genetic payloads. Focus areas include engineering specificity and programmability of recognition elements, enabling large-fragment DNA insertion and methods intended for use in mammalian cells. Cambridge-based, founded mid-2023.

Industries

biotechnology
genetics

Nr. of Employees

small (1-50)

Gene Weaver

Suite 9, Science Village, Chesterford Research Park, Little Chesterford, Essex CB10 1XL


Products

Programmable gene insertion platform (naturally derived enzymatic system)

A platform based on a naturally occurring enzymatic system engineered for programmable recognition, controlled cutting, and precision insertion of large genetic payloads.


Services

Partnership-based collaborations to integrate intracellular delivery methods with programmable gene insertion technology, including development of optimized delivery workflows.

Expertise Areas

  • Programmable gene insertion
  • Enzymatic gene editing
  • Large-fragment DNA insertion
  • Assay development for nucleic acid recombination
  • Show More (5)

Key Technologies

  • Programmable enzymatic insertion platform
  • Large-fragment DNA insertion
  • Non-DSB insertion methods
  • In vitro recombination assays
  • Show More (4)

News & Updates

Strategic collaboration to integrate an intracellular delivery platform with a programmable gene insertion technology for optimized delivery of multi-component cargos in mammalian cells.

Award of $515,214 from the Gates Foundation to investigate programmable gene insertion activity in mammalian cells and advance the platform for gene therapy applications.


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