Echelon Biosciences


Echelon Biosciences is dedicated to developing research reagents and assays that lead to diagnostics and drug treatments for diseases, with a focus on Lipid and Cell Signaling. They aim to drive scientific progress by providing high-quality solutions, collaborating with scientists, and supporting complex research challenges.

Industries

Biopharma
Biotechnology
Life Science
Biotechnology Research

Nr. of Employees

small (1-50)

Echelon Biosciences


Products

Research-grade cardiolipin (16:0) reagent

Purified cardiolipin (16:0) supplied for research use with specified purity, storage conditions and technical data sheet.

Lyso-phosphatidylethanol (16:0 LysoPEth) standard

Research-grade LysoPEth (16:0) supplied as a biomarker standard for LC-MS workflows with technical data sheet and storage instructions.

LysoPE (16:0 LPE) research lipid

Purified lysophosphatidylethanolamine (16:0) for use in cell signaling and lipid mediator studies with associated technical documentation.

Catalog of ionizable and cationic lipids

Catalog supply of multiple research ionizable/cationic lipids commonly used for LNP formulation and research screening of nucleic-acid delivery.

Purified Anti-Phosphatidylethanol (PEth) antibody

Affinity-purified antibody reactive primarily with phosphatidylethanol, validated for ELISA and fluorescence microscopy, supplied with storage and handling guidance.

Tetramethylrhodamine-conjugated anti-PI(4,5)P2 antibody (TMR)

Monoclonal antibody against PI(4,5)P2 conjugated to a tetramethylrhodamine fluorophore for immunofluorescence and ELISA applications, supplied at defined concentration ranges.

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Services

Formulation and optimization of LNPs including ionizable lipid selection, microfluidic mixing, encapsulation efficiency testing, and pre-screening in cell culture.

Turnkey execution of validated research-use assays with sample receipt and handling, data analysis and QA with certificate of analysis.

Custom synthesis of complex lipids, phospholipids, sphingolipids, small heterocycles, peptides and isotope-labeled standards with purification and analytical support; scale-up from milligram to multigram quantities.

In vitro transcription production of mRNA cargos with co-transcriptional capping, optional modified nucleotides and downstream purification tailored for formulation projects.

Production of nanobodies and antibodies, including affinity purification, conjugation to labels, and technical support for integrating reagents into assays.

Design and development of custom assays, custom microplate and bead coatings, and bespoke bioconjugation to support novel assay formats or reagent capture needs.

Expertise Areas

  • Lipid chemistry and specialty lipid synthesis
  • Lipid nanoparticle formulation and screening
  • mRNA in vitro transcription for research applications
  • Assay development and contract assay execution (ELISA, AlphaScreen)
  • Show More (8)

Key Technologies

  • Ionizable and cationic lipid synthesis
  • Lipid nanoparticles (LNPs)
  • In vitro transcription (IVT) for mRNA
  • Microfluidic mixing for LNP formulation
  • Show More (11)

News & Updates

VION Biosciences expands its platform and product line through acquisition of Echelon Biosciences.

Echelon Biosciences is now listed in the NIH Glycoscience Common Fund Program.

Echelon showcased at Utah’s Life Sciences Industry event.

Echelon announces distribution partnership with ProBioscience Technologies.

Recognition for Echelon’s ELISA products.

Celebrating 25 years of scientific contributions.

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