CysBio
Cysbio is a biotechnology company focused on designing and constructing microbial cell factories for industrial production of biochemicals using fermentation and biocatalysis. They utilize advanced metabolic engineering and synthetic biology approaches to produce commodity chemicals and develop new chemicals with novel properties, aiming to create sustainable and environmentally friendly solutions.
Industries
Nr. of Employees
small (1-50)
CysBio
Patents
Process for the production of sulfated phenolic compounds using modified Escerichia coli
US-11555212-B2
View DetailsGenetically modified microorganisms having improved tolerance towards L-serine
US-11407976-B2
View DetailsProcesses for the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity
US-11306331-B2
View DetailsModified Escherichia coli having an increased expression of a CysP transporter, an ATP sulfurylase, an APS kinase and a PAP phosphatase
US-10954536-B2
View Details
Process for the production of sulfated phenolic compounds using modified Escerichia coli
US-11555212-B2
View DetailsGenetically modified microorganisms having improved tolerance towards L-serine
US-11407976-B2
View DetailsProcesses for the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity
US-11306331-B2
View DetailsModified Escherichia coli having an increased expression of a CysP transporter, an ATP sulfurylase, an APS kinase and a PAP phosphatase
US-10954536-B2
View DetailsProducts
Fermentation-derived amino acids
Selected amino acids produced via engineered microbial fermentation with optimized strains and downstream purification, intended for feed, food, pharma and industrial polymer applications.
Sulfated phenolic biochemicals (enzymatic sulfation)
Sulfated phenolic compounds produced via a microbial enzymatic sulfation platform to create water-soluble, less-toxic or novel-function molecules for use as antifouling agents, additives or specialty monomers.
Fermentation-derived amino acids
Selected amino acids produced via engineered microbial fermentation with optimized strains and downstream purification, intended for feed, food, pharma and industrial polymer applications.
Sulfated phenolic biochemicals (enzymatic sulfation)
Sulfated phenolic compounds produced via a microbial enzymatic sulfation platform to create water-soluble, less-toxic or novel-function molecules for use as antifouling agents, additives or specialty monomers.
Services
Development and optimization of fermentation processes, media and bioreactor operation; transfer to pilot-scale facilities and scale-up to multi-m3 volumes.
Genetic design and construction of production strains using plasmid systems and genome editing to enhance pathway flux and production stability.
Design and iterative optimization of purification workflows to isolate target amino acids and small molecules at pilot scale with focus on yield and product definition.
Chemical and chromatographic analysis of fermentation samples and purified products to support process monitoring and product quality assessment.
Development of regulatory roadmaps for registrations such as REACH and preparation of data packages required for feed/food registration, in collaboration with regulatory experts.
Collaboration with downstream formulators and industrial partners to test, modify and integrate biologically produced compounds into commercial products and coatings.
Development and optimization of fermentation processes, media and bioreactor operation; transfer to pilot-scale facilities and scale-up to multi-m3 volumes.
Genetic design and construction of production strains using plasmid systems and genome editing to enhance pathway flux and production stability.
Design and iterative optimization of purification workflows to isolate target amino acids and small molecules at pilot scale with focus on yield and product definition.
Chemical and chromatographic analysis of fermentation samples and purified products to support process monitoring and product quality assessment.
Development of regulatory roadmaps for registrations such as REACH and preparation of data packages required for feed/food registration, in collaboration with regulatory experts.
Collaboration with downstream formulators and industrial partners to test, modify and integrate biologically produced compounds into commercial products and coatings.
Expertise Areas
- Metabolic engineering
- Microbial fermentation and scale-up
- Strain and protein engineering
- Enzymatic sulfation and sulfated phenolic chemistry
Key Technologies
- Metabolic engineering
- Synthetic biology
- Enzymatic sulfation
- Microbial fermentation
News & Updates
Development of a cell-based manufacturing system for renewable production of sulfated compounds, including the bio-based antifouling agent zosteric acid (ZA-bio). The project aims to replace toxic antifouling paints with eco-friendly alternatives.
Cysbio has advanced a bio-based platform for amino acid production, which is more economical and environmentally friendly, using genetically modified bacterial strains for fermentation from renewable sources.
Successfully scaled fermentation process to 15 m3, with ongoing process development for downstream purification and product application testing.
Development of a cell-based manufacturing system for renewable production of sulfated compounds, including the bio-based antifouling agent zosteric acid (ZA-bio). The project aims to replace toxic antifouling paints with eco-friendly alternatives.
Cysbio has advanced a bio-based platform for amino acid production, which is more economical and environmentally friendly, using genetically modified bacterial strains for fermentation from renewable sources.
Successfully scaled fermentation process to 15 m3, with ongoing process development for downstream purification and product application testing.