Syngulon
Syngulon is a synthetic biology startup developing original genetic technologies using bacteriocins to improve microbial fermentation. Their mission is to provide genetic technologies that make microbial strains involved in industrial processes safer and more efficient, focusing on antibiotic-free selection and contamination prevention in biotechnological applications.
Industries
Products
Bacteriocin gene library (PARAGEN collection)
A curated DNA library of natural and synthetic bacteriocin genetic elements organized for industrial application; supports rapid synthesis, testing and combination use to shape microbial communities.
Antibiotic-free selection system for E. coli fermentation (plasmid-based)
A plasmid-based bacteriocin/immunity selection system for recombinant protein and plasmid DNA production in E. coli that avoids antibiotic resistance markers and reports increased plasmid stability and product yield.
Bacteriocin gene library (PARAGEN collection)
A curated DNA library of natural and synthetic bacteriocin genetic elements organized for industrial application; supports rapid synthesis, testing and combination use to shape microbial communities.
Antibiotic-free selection system for E. coli fermentation (plasmid-based)
A plasmid-based bacteriocin/immunity selection system for recombinant protein and plasmid DNA production in E. coli that avoids antibiotic resistance markers and reports increased plasmid stability and product yield.
Services
Customization of bacteriocins for fermentation selection and contamination control
Design and provision of bacteriocins or bacteriocin combinations tailored to specific contaminant profiles or production strain requirements; includes metagenomic-informed selection.
Licensing of antibiotic-free selection and bacteriocin technologies
Non-exclusive licensing of issued patents and patent applications covering bacteriocin/immunity selection circuits and engineered antimicrobial peptides for industrial use.
R&D collaborations for bacteriocin discovery and scale-up
Collaborative research programs with academic and industrial partners to discover, optimize and scale bacteriocin-based solutions for specific applications.
Modelling and predictive services for microbial consortia
Computational modelling services to predict the dynamics of microbial communities and the impact of bacteriocin interventions to inform design and deployment strategies.
Customization of bacteriocins for fermentation selection and contamination control
Design and provision of bacteriocins or bacteriocin combinations tailored to specific contaminant profiles or production strain requirements; includes metagenomic-informed selection.
Licensing of antibiotic-free selection and bacteriocin technologies
Non-exclusive licensing of issued patents and patent applications covering bacteriocin/immunity selection circuits and engineered antimicrobial peptides for industrial use.
R&D collaborations for bacteriocin discovery and scale-up
Collaborative research programs with academic and industrial partners to discover, optimize and scale bacteriocin-based solutions for specific applications.
Modelling and predictive services for microbial consortia
Computational modelling services to predict the dynamics of microbial communities and the impact of bacteriocin interventions to inform design and deployment strategies.
Expertise Areas
- Antibiotic-free selection systems for biomanufacturing
- Bacteriocin discovery, engineering and library development
- Recombinant protein and plasmid DNA production workflows
- Microbial fermentation scale-up and bioprocess development
Key Technologies
- Bacteriocin-based selection systems
- Plasmid-based antibiotic-free selection
- Synthetic biology for peptide design and engineering
- Cell-free protein/peptide synthesis