Csa Biotechnologies


CSA BioTech is a clinical stage therapeutic development company focused on developing ceragenin-based therapeutics. They aim to provide a superior defense against drug-resistant infections and diseases by harnessing the body's innate immune system with their platform technology of ceragenins, which are synthetic small molecules mimicking endogenous antimicrobial peptides. Their mission is to create safe, effective, and scalable antimicrobial and regenerative agents to combat resistant pathogens, promote tissue repair, and improve health outcomes.

Industries

biotechnology
therapeutics

Nr. of Employees

small (1-50)

Csa Biotechnologies

Spanish Fork, Utah, United States, North America


Products

Therapeutic candidates based on cationic small-molecule peptide mimetics

Clinical-stage therapeutic candidates derived from a platform of small-molecule, membrane-active mimetics of host-defense peptides intended for treatment of chronic wounds and other indications.

Topical and device-directed antifungal formulations

Formulated gel and cream candidates intended for topical eradication of fungal infections in skin and mucosal tissues, evaluated in ex vivo and in vitro models.


Services

Preclinical development services for antimicrobial candidates

Design and execution of in vitro and in vivo preclinical studies to evaluate antimicrobial efficacy, antibiofilm activity, and regenerative endpoints.

Formulation and delivery development

Formulation of small-molecule antimicrobials into micelles, gels, creams, and coatings for topical and device applications, including controlled-release testing from delivery matrices.

Device coating development and preclinical testing

Development of antimicrobial coatings for medical devices (e.g., endotracheal tubes) with in vitro colonization assays and large-animal tolerability testing.

Analytical and mechanistic assay services

Antimicrobial susceptibility testing, biofilm assays, microscopy, spectroscopy, and nanomechanical measurements to characterize antimicrobial action and resistance profiles.

Expertise Areas

  • Antimicrobial therapeutics development
  • Preclinical in vivo efficacy and safety studies
  • Formulation and topical/device delivery systems
  • Antifungal and antibiofilm research
  • Show More (5)

Key Technologies

  • Small-molecule mimetics of host-defense peptides
  • Micellar/polymer (poloxamer) formulations
  • Hydrogel/film device coatings with controlled elution
  • Core-shell magnetic nanoparticles (functionalized MNPs)
  • Show More (6)

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