Kinnear Pharmaceuticals


Kinnear Pharmaceuticals is a preclinical stage company focused on developing innovative Ceragenin-based treatments for diseases lacking effective solutions. As a subsidiary of N8 Biosciences, it aims to pioneer anti-infective and anti-inflammatory therapies, leveraging proprietary technology based on Dr. Paul B. Savage’s research. The company’s mission is to discover, develop, and bring to market revolutionary product candidates, with a focus on combating resistant infections, biofilms, and inflammatory conditions.

Industries

biopharma
biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

Kinnear Pharmaceuticals

3960 Howard Hughes Parkway, Las Vegas, NV, 89169


Products

Inhaled membrane-targeting antimicrobial candidate for cystic fibrosis

Preclinical small-molecule inhaled therapeutic candidate developed to restore antimicrobial activity in cystic fibrosis airways and treat/prevent pulmonary infections caused by Gram-negative and fungal pathogens.

Drug-eluting coated endotracheal tube for prevention of ventilator-associated pneumonia

Medical device project involving a small-molecule drug-eluting coating applied to endotracheal tubes to prevent biofilm formation and reduce ventilator-associated pneumonia in mechanically ventilated patients; subject of ongoing clinical evaluation.

Coated indwelling-device projects (hemodialysis catheters, pacemaker envelopes, pedicle screws)

Development projects for application of antimicrobial drug-eluting coatings to various indwelling devices to reduce hospital-acquired infections, supported by SBIR grant funding.


Services

Preclinical program development including in vitro efficacy testing, biofilm and resistance assessments, proteomics-based mechanism studies, and preparation for regulatory interactions.

Expertise Areas

  • Antimicrobial drug development
  • Anti-biofilm therapeutics
  • Drug-eluting medical device coatings
  • Preclinical development and translational research
  • Show More (4)

Key Technologies

  • Membrane-targeting antimicrobial agents
  • Antimicrobial peptide mimetics
  • Drug-eluting coating technology for medical devices
  • Inhaled drug formulation
  • Show More (4)

News & Updates

FDA QiDP designation is a significant milestone for Kinnear Pharmaceuticals, recognizing the importance of CSA-131 in treating Pseudomonas infections in cystic fibrosis patients.

A peer-reviewed publication reports on the efficacy of Ceragenin CSA-131 against Candida auris, a serious global health threat.

Colistin, a last-resort antibiotic, is facing resistance issues as a transferrable gene conferring resistance has been identified.

Research by Professor Jordi Vila shows CSA-131 is effective against colistin-resistant bacterial strains.


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