Corvus Biomedical


CorVus Biomedical is dedicated to discovering new treatments, pharmaceuticals, medical devices, and surgical techniques to minimize or eliminate long-term complications of obesity, diabetes, and other diseases. They produce unique miniature Ossabaw swine models that mimic human symptoms and diseases, which are used to test new medical devices, pharmaceuticals, and surgical techniques. The company also supports research and education through the non-profit CorVus Foundation, focusing on reducing obesity, diabetes, and cardiovascular disease.

Industries

biopharma
biotechnology
transportation

Nr. of Employees

small (1-50)

Corvus Biomedical

Crawfordsville, Indiana, United States, North America


Products

Miniature Ossabaw swine research models

Large-animal models exhibiting a thrifty-gene phenotype prone to obesity, reversible prediabetic states, and metabolic syndrome used for translational research across multiple specialties.


Services

Production and husbandry services to maintain closed Ossabaw miniature swine colonies, including vaccination and health monitoring.

Conducting preclinical studies on-site including surgical models, device evaluation, and experimental procedures in large-animal models.

Execution of pharmacokinetic and related analytical studies in large-animal models to inform preclinical development.

Climate-controlled transport of research animals with pre-shipment veterinary inspection and in-transit care for domestic and international deliveries.

Expertise Areas

  • Translational large-animal disease modeling
  • Metabolic disease and obesity research
  • Preclinical pharmacology and pharmacokinetics
  • Preclinical device and surgical procedure evaluation
  • Show More (4)

Key Technologies

  • Large-animal gene editing
  • In vivo pharmacokinetic/pharmacodynamic studies
  • Preclinical device and interventional testing
  • Translational metabolic disease modeling
  • Show More (3)

News & Updates

Research on animal model and translational interventions

Michael Sturek, MS, PhD, presented CorVus Biomedical's research on their innovative animal model and its uses in exploring translational interventions such as cryolipolysis, insulin pharmacodynamics, coronary stenting, and vascular targeting and imaging. Also introduced gene editing of Ossabaw miniature pigs.


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