ChemDiv
ChemDiv is a global leader in discovery chemistry, offering a vast collection of small molecules and building blocks for drug discovery. They utilize modern structure-based discovery chemistry and AI/ML technologies to add novel compounds at a rate of 50,000 molecules per year. ChemDiv provides access to pre-plated annotated libraries, custom targeted libraries, and a variety of screening sets for multiple targets and industries. With over 29 years of experience, they have delivered hundreds of leads, drug candidates, and new drugs across various therapeutic areas.
Industries
Nr. of Employees
large (251-1000)
ChemDiv
12730 High Bluff Dr, Suite 100, San Diego, CA 92130, USA
Patents
Products
Screening compound libraries
Commercial collections of small-molecule screening libraries including focused, annotated, diversity, antiviral and target-specific libraries available for download and purchase.
Chemical building blocks catalog
A searchable catalog of building blocks and reagents with compound-specific metadata (molecular weight, formula, CAS, MFCD, SMILES) available in multiple pack sizes.
Pre-configured antiviral and target-focused sets
Pre-assembled libraries targeted to antiviral proteases, viral entry factors and other target classes (examples include 3CLpro, PLpro, ACE2 and broader coronavirus-related sets).
Screening compound libraries
Commercial collections of small-molecule screening libraries including focused, annotated, diversity, antiviral and target-specific libraries available for download and purchase.
Chemical building blocks catalog
A searchable catalog of building blocks and reagents with compound-specific metadata (molecular weight, formula, CAS, MFCD, SMILES) available in multiple pack sizes.
Pre-configured antiviral and target-focused sets
Pre-assembled libraries targeted to antiviral proteases, viral entry factors and other target classes (examples include 3CLpro, PLpro, ACE2 and broader coronavirus-related sets).
Services
Custom synthesis, building-block supply and scale-up chemistry services to support medicinal chemistry and CMC needs.
Medicinal chemistry project support for hit-to-lead and lead optimization activities.
Computational chemistry services including virtual screening, 3D-shape similarity, and structure-based hit selection.
Assay development, target-based and phenotypic screening, and biological evaluation services including ex vivo and in vivo models.
Preclinical ADME, pharmacokinetics, and toxicology testing to support selection and safety profiling of compounds.
Customization of focused or pre-designed libraries and delivery in requested plate formats or compound formats (solutions or dry powders).
Custom synthesis, building-block supply and scale-up chemistry services to support medicinal chemistry and CMC needs.
Medicinal chemistry project support for hit-to-lead and lead optimization activities.
Computational chemistry services including virtual screening, 3D-shape similarity, and structure-based hit selection.
Assay development, target-based and phenotypic screening, and biological evaluation services including ex vivo and in vivo models.
Preclinical ADME, pharmacokinetics, and toxicology testing to support selection and safety profiling of compounds.
Customization of focused or pre-designed libraries and delivery in requested plate formats or compound formats (solutions or dry powders).
Expertise Areas
- Integrated target-to-clinic drug discovery
- Library design and curation
- Medicinal chemistry and custom synthesis
- Structure-based computational chemistry (CADD)
Key Technologies
- Virtual screening (3D shape similarity, APF)
- Structure-based drug design
- Cheminformatics filtering (REOS, PAINS, Tanimoto)
- Hybrid AI/ML for dataset curation
News & Updates
Gossamer Bio will present clinical and preclinical data at the 2025 Congress.
ChemDiv’s proprietary library was a source of selective inhibitors targeting immune checkpoints.
ChemDiv’s research and discoveries are featured in scientific publications and patents.
A publication in Nature discusses neurophysiological research involving chemdiv compounds.
Research on molecular diversity and fingerprinting techniques.
Gossamer Bio will present clinical and preclinical data at the 2025 Congress.
ChemDiv’s proprietary library was a source of selective inhibitors targeting immune checkpoints.
ChemDiv’s research and discoveries are featured in scientific publications and patents.
A publication in Nature discusses neurophysiological research involving chemdiv compounds.
Research on molecular diversity and fingerprinting techniques.