Cardurion Pharmaceuticals, Inc.


Cardurion is a next-generation cardiovascular company dedicated to addressing unmet needs in heart disease through innovative therapeutics. Founded by physician-scientists, it focuses on groundbreaking clinical programs targeting heart failure and other cardiovascular diseases, leveraging world-class expertise in cardiovascular signaling pathways to develop novel treatments and improve patient outcomes.

Industries

biotechnology
health-care
medical
pharmaceutical

Nr. of Employees

small (1-50)

Cardurion Pharmaceuticals, Inc.

78 Blanchard Road, Suite 200, Burlington, MA 01803, USA


Patents

PDE9 inhibitors for treating sickle cell disease

US-12213975-B2

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Monohydrate and crystalline forms of 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one

US-12006319-B2

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Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one

US-11999741-B2

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Substituted imidazo[1,2-b]pyridazines and [1,2,4]triazolo[4,3-b]pyridazines as CaMKII inhibitors

US-11795172-B2

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Process for the synthesis of 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one

US-11370795-B2

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Substituted amines for treating cardiac diseases

US-11197858-B2

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Products

PDE9 Inhibitor

A treatment under development for both types of chronic heart failure, HFrEF and HFpEF, aiming to improve efficacy when added to existing medical therapies.

CaMKII Inhibitor

A drug in clinical trials targeting hyperactivated CaMKII, intended to treat various cardiovascular diseases including CPVT, heart failure, and atrial fibrillation.

Clinical Trials

Research studies designed to evaluate the safety and efficacy of Cardurion's investigational medicines for cardiovascular diseases.

Medicinal Chemistry and Molecular Biology Services

Specialized services in medicinal chemistry, computational molecular modeling, and genetic engineering to support cardiovascular research.


News & Updates

Cardurion announced a private investment of up to $300 million from Polaris Partners, supporting its growth and pipeline development in cardiovascular therapeutics.

Marcia Moore joins Cardurion with over 30 years of pharmaceutical and biotech leadership experience to support pipeline advancement.

The company has commenced dosing patients in a large-scale trial to evaluate CRD-740 for heart failure treatment.

FDA accepted the IND for CRD-733, and a Phase 1 trial has been initiated to evaluate safety and pharmacodynamics.


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