Basecamp Bio
Provider of integrated enabling capabilities for cell and gene therapies, combining gene-editing discovery and engineering with process development, cGMP manufacturing, analytical and regulatory support, and partnerships to accelerate development and manufacturing of genetic medicines.
Industries
Nr. of Employees
small (1-50)
Products
Lentiviral vector production platform (suspension-based)
A suspension-culture lentiviral vector manufacturing platform designed for scalable production from research to GMP supply, with customizable processes for partner needs.
Diverse gene editing enzyme collection and modular base editor systems
A curated collection of small, diverse RNA-guided nucleases and engineered base editors intended to expand genomic target coverage and enable allele-selective and multiplex editing.
LNP delivery research platform
An LNP research platform focused on tissue targeting and de-targeting capabilities to support in vivo nucleic acid and gene editing delivery strategies.
Internal NGS core and bioinformatics platform
Sequencing infrastructure and analysis pipelines to support genomic characterization, QC, and data-quality requirements for R&D and manufacturing.
Investigational allele-selective gene editing therapeutic (preclinical/early development)
An internal program advancing allele-selective gene editing approaches for neurological disease using targeted nuclease and base-editing strategies validated in preclinical models.
Lentiviral vector production platform (suspension-based)
A suspension-culture lentiviral vector manufacturing platform designed for scalable production from research to GMP supply, with customizable processes for partner needs.
Diverse gene editing enzyme collection and modular base editor systems
A curated collection of small, diverse RNA-guided nucleases and engineered base editors intended to expand genomic target coverage and enable allele-selective and multiplex editing.
LNP delivery research platform
An LNP research platform focused on tissue targeting and de-targeting capabilities to support in vivo nucleic acid and gene editing delivery strategies.
Internal NGS core and bioinformatics platform
Sequencing infrastructure and analysis pipelines to support genomic characterization, QC, and data-quality requirements for R&D and manufacturing.
Investigational allele-selective gene editing therapeutic (preclinical/early development)
An internal program advancing allele-selective gene editing approaches for neurological disease using targeted nuclease and base-editing strategies validated in preclinical models.
Services
cGMP manufacturing and automated production services
On-site manufacture of clinical- and commercial-stage cell and gene therapy materials within cGMP suites, supported by automated and digital workflows for scale-up.
Process development and scale-up services
Process design and optimization for upstream and downstream unit operations with transfer readiness to GMP manufacturing.
Analytical and potency assay development services
Development, qualification, and validation of analytical methods and potency assays to support regulatory submissions and product release.
NGS and bioinformatics services
Sequencing, data processing, and bioinformatics to support R&D, QC, and release testing workflows.
Gene editing discovery and protein engineering services
Discovery, characterization, and engineering of novel nucleases and base editors, plus computational design and experimental optimization services for editing systems.
Regulatory CMC and quality support services
Regulatory strategy, CMC documentation, and quality-system support to prepare regulatory filings and maintain manufacturing compliance.
cGMP manufacturing and automated production services
On-site manufacture of clinical- and commercial-stage cell and gene therapy materials within cGMP suites, supported by automated and digital workflows for scale-up.
Process development and scale-up services
Process design and optimization for upstream and downstream unit operations with transfer readiness to GMP manufacturing.
Analytical and potency assay development services
Development, qualification, and validation of analytical methods and potency assays to support regulatory submissions and product release.
NGS and bioinformatics services
Sequencing, data processing, and bioinformatics to support R&D, QC, and release testing workflows.
Gene editing discovery and protein engineering services
Discovery, characterization, and engineering of novel nucleases and base editors, plus computational design and experimental optimization services for editing systems.
Regulatory CMC and quality support services
Regulatory strategy, CMC documentation, and quality-system support to prepare regulatory filings and maintain manufacturing compliance.
Expertise Areas
- Gene editing and base editing
- Computational biology and AI-driven protein engineering
- High-throughput screening and robotics for protein/nuclease optimization
- cGMP manufacturing for cell and gene therapies
Key Technologies
- Next-generation sequencing (NGS)
- RNA-guided nucleases (RGNs) and CRISPR-type systems
- Base editing (adenine and cytosine deaminase-based editors)
- Lipid nanoparticle (LNP) delivery systems